221148-46-5 Usage
Chemical class
Pyrazolo[1,5-b]pyridazine
A synthetic chemical compound with potential pharmaceutical applications.
Ethoxyphenyl group
4-ethoxyphenyl
A phenyl ring connected to an ethoxy (ethyl ether) group.
Methylsulfonylphenyl group
4-mesylphenyl (incorrect term, should be 4-methylsulfonylphenyl)
A phenyl ring connected to a methylsulfonyl group.
Potential applications
Drug candidate for various diseases
Studied for its potential use in treating diseases like cancer and inflammatory disorders.
Unique structure
Important for drug development
The compound's structure contributes to its potential biological activities and usefulness in medicinal chemistry.
Biological activities
Potential valuable tool for research
The compound's biological activities make it a promising subject for further research in pharmacology and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 221148-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,1,4 and 8 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 221148-46:
(8*2)+(7*2)+(6*1)+(5*1)+(4*4)+(3*8)+(2*4)+(1*6)=95
95 % 10 = 5
So 221148-46-5 is a valid CAS Registry Number.
221148-46-5Relevant articles and documents
Efficient synthesis of the selective COX-2 inhibitor GW406381X
Whitehead, Andrew J.,Ward, Richard A.,Jones, Martin F.
, p. 911 - 913 (2007)
An efficient synthesis of the selective COX-2 inhibitor GW406381X is described via a novel intramolecular Mannich-type cyclisation to construct the pyrazolo-[1,5a]-pyridazine heterocyclic core.
Process for the preparation of pyrazolopyridine derivatives
-
, (2008/06/13)
The invention provides a process for preparing a compound of formula (I) and pharmaceutically acceptable derivatives thereof in which: R0 is halogen, C1-6alkyl, C1-6alkoxy, C1-6alkoxy substituted by one or more fluorine atoms, or O(CH2)nNR4R5; R1 and R2 a
