221177-68-0Relevant academic research and scientific papers
Synthesis and cytotoxicity evaluation of a novel justicidin G analogue and its phosphate ester
Wang, Sheng-Peng,Tong, Yuan-Feng,Wang, Dong-Mei,Wang, Nan,Yan, Zheng,Huang, Ping,Wu, Song
, p. 1044 - 1046 (2014/08/18)
The novel justicidin G analogue 13 and its phosphate ester 15 were synthesized as potential anticancer agents in several steps starting from commercially available methyl gallate and veratraldehyde. The cytotoxicity of the intermediates was tested against HCT-8, BEL-7402, KETR3, HELA, BGC-823, KB and MCF-7 cell lines by the MTT test, and compound 15 exhibited significant cytotoxicity in HELA and KB cell lines.
Synthesis of an antioxidant having a dibenz[b,f]oxepine skeleton
Jinno, Shuji,Okita, Takaaki
, p. 303 - 314 (2007/10/03)
Dibenz[b,f]oxepine derivative (1) isolated from a yeast as an antioxidant was synthesized via 17 reaction steps starting from methyl gallate. However, the physicochemical data of the synthetic compound (1) were different from the previously reported values. Moreover, the antioxidative activity of the synthetic 1 was slightly more active than that of the natural product.
