2212-47-7Relevant academic research and scientific papers
Evidence for mono- and bisdentate boronate complexes of glucose in the furanose form. Application of 1Jc-c coupling constants as a structural probe
Norrild, Jens Chr.,Eggert, Hanne
, p. 1479 - 1484 (1995)
Complex formation between aromatic boronic acids and D-glucose was investigated by 1H and 13C NMR spectroscopy both under neutral nonaqueous and alkaline aqueous conditions. The structure of the bisdentate complex between 2,2′-dimethoxydiphenylmethane-5,5′-diboronic acid and glucose was reinvestigated and reassigned. The reactions studied are shown in Scheme 1. The complexes contain in all cases the furanose form of glucose bound to two boronic acid groups where the one is bound in the (1,2) position. The binding site for the second boronic acid group is (3,5) under neutral nonaqueous conditions. In aqueous alkaline solution the second binding site varies from the mono- to the diboronic acid. The second monoboronic acid binds to the (3,5,6) position in a tris coordinating manner, and the diboronic acid binds its second boronic acid group only to the (5,6) position. Two closely related complexes (ratio 4:1) are observed in the spectra with the monoboronic acid. This is ascribed to diastereomerism from the 1,2-complexed stereocenter. 1Jc-c are used in the structure assignment. Exceptionally low values of 34-35 Hz for 1Jc-c are measured for vicinal diols when the O-C-C-O fragment becomes incorporated in a five membered ring as is the case in cyclic boronic esters with a vicinal ester bonding.
Functional Ionic Liquids as Efficient and Recyclable Catalysts for the Methylation of Formaldehyde with Aromatics
Song, Heyuan,Jin, Fuxiang,Jin, Ronghua,Kang, Meirong,Li, Zhen,Chen, Jing
, p. 1264 - 1272 (2016/07/06)
Abstract: Methylation of formaldehyde with various aromatics under functional ionic liquids catalysis has been developed. Among the ionic liquids investigated, triphenyl-(4-sulfobutyl)-phosphonium triflate ([TTPBs][CF3SO3]) showed high activity and afforded excellent yields of diarylmethane derivatives. A mechanism for the catalytic performance of [TTPBs][CF3SO3] is proposed. Besides, the catalyst can simply be separated from the reaction mixture by centrifugation and be recycled ten times without noticeable loss of activity. Graphical Abstract: Diarylmethane derivatives were successfully synthesized from the methylation of formaldehyde with aromatics using efficient and recyclable functional ionic liquids as catalysts, excellent yields and selectivities were obtained under solvent free conditions. The catalyst was reused at least ten consecutive recycles without noticeable loss in its catalytic activity. Meanwhile, the usability of catalyst was explored.[Figure not available: see fulltext.]
Acid-promoted rearrangement of arylmethyl azides: Applications toward the synthesis of N-arylmethyl arenes and polycyclic heteroaromatic compounds
Tummatorn, Jumreang,Thongsornkleeb, Charnsak,Ruchirawat, Somsak
experimental part, p. 4732 - 4739 (2012/07/28)
An acid-promoted Aubé-Schmidt's rearrangement of arylmethyl azides provides a useful in situ iminium ion intermediate, which can be efficiently trapped by various nucleophiles. We report here the reaction of this iminium ion with aromatic nucleophiles to
Specific Complexation of Glucose with a Diphenylmethane-3,3'-diboronic Acid Derivative: Correlation between the Absolute Configuration of Mono- and Di-saccharides and the Circular Dichroic Activity of the Complex
Shiomi, Yutaka,Saisho, Miwako,Tsukagoshi, Kazuhiko,Shinkai, Seiji
, p. 2111 - 2118 (2007/10/02)
For the development of receptor molecules that can precisely recognize sugar molecules, we recently synthesized bis-(6-methoxyphenyl)methane-3,3'-diboric acid 2.This compound forms 1:1 complexes with mono- and di-saccharides and gives circular dichroism (
A SIMPLE AND INEXPENSIVE PROCEDURE FOR CHLOROMETHYLATION OF CERTAIN AROMATIC COMPOUNDS
McKillop, Alexander,Madjdabadi, Fereidon Abbasi,Long, David A.
, p. 1933 - 1936 (2007/10/02)
Reaction of a range of aromatic compounds with methoxyacetyl chloride and aluminium chloride in either nitromethane or carbon disulphide results in chloromethylation in good to excellent yield.
