22120-36-1

Basic information

• Product Name: 5-FLUORO-N,N-DIMETHYLTRYPTAMINE
• Synonyms: 5-FLUORO-N,N-DIMETHYLTRYPTAMINE
• CAS NO: 22120-36-1
• Molecular Formula: C12H15FN2
• Molecular Weight: 206.26
• Mol File: 22120-36-1.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 335.7 °C at 760 mmHg
• Flash Point: 156.8 °C
• Appearance: /
• Density: 1.151 g/cm³
• Vapor Pressure: 0.000118mmHg at 25°C
• Refractive Index: 1.597
• CAS DataBase Reference: 5-FLUORO-N,N-DIMETHYLTRYPTAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-FLUORO-N,N-DIMETHYLTRYPTAMINE(22120-36-1)
• EPA Substance Registry System: 5-FLUORO-N,N-DIMETHYLTRYPTAMINE(22120-36-1)

Safety Data

• Hazardous Substances Data: 22120-36-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15FN2/c1-15(2)6-5-9-8-14-12-4-3-10(13)7-11(9)12/h3-4,7-8,14H,5-6H2,1-2H3

Upstream product

• 19718-92-4 4-(N,N-dimethylamino)butyraldehyde dimethyl acetal 
• 823-85-8 4-fluorophenyhydrazine hydrochloride 
• 50-00-0 formaldehyd 
• 576-16-9 5-fluorotryptamine 
• 1256348-68-1 5-fluoro-3-(2-hydroxyethyl)-1H-indole methanesulfonate 
• 124-40-3 dimethyl amine 

Downstream Products

• 1375501-79-3 C₁₉H₁₉BrClFN₂ 

Relevant articles and documents

Indole derivatives and its application on the medicament

The invention provides indole derivatives or stereisomers, tautomers, nitrogen oxides, solvate, metabolic products, pharmaceutically acceptable salts or prodrugs thereof for treating the alzheimer disease. The invention further discloses a pharmaceutical composition containing the compounds and a method of using the compounds or the pharmaceutical composition thereof to treat the alzheimer disease.

3-ALKYL-5-FLUOROINDOLE DERIVATIVES AS MYELOPEROXIDASE INHIBITORS

The invention relates to a compound of formula (Ia) wherein n is an integer between 2 and 10, R1 and R2 independently represent a substituent selected from the group consisting of hydrogen, C1-C10 alkyl, C3-C10 cycloalkyl and aminoalkyl, or R1 and R2 are taken together with the nitrogen atom to which they are attached to form a four to ten-membered heterocycle, R5 represents independently in each of the n units a substituent selected from the group consisting of hydrogen, C1-C10 alkyl, halogen, alkoxy, aminoalkyl and alkylamino; or a pharmaceutically acceptable salt thereof, with the proviso that the 5-fluorotryptamine is excluded, for the treatment or the prophylaxis of neuroinflammatory diseases or disorders. The invention also relates to a pharmaceutical composition, a method for inhibiting myeloperoxidase enzyme activity, to a method for inhibiting Low density lipoproteins oxidation.

Improved Fischer indole reaction for the preparation of N,N-dimethyltryptamines: Synthesis of L-695-894, a potent 5-HT(1D) receptor agonist

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