221298-01-7

Basic information

• Product Name: (4-bromopyridine-2,6-diyl)bis(methylene) bis(4-methylbenzenesulfonate)
• Synonyms: (4-bromopyridine-2,6-diyl)bis(methylene) bis(4-methylbenzenesulfonate)
• CAS NO: 221298-01-7
• Molecular Weight: 526.429
• Mol File: 221298-01-7.mol

Chemical Properties

• CAS DataBase Reference: (4-bromopyridine-2,6-diyl)bis(methylene) bis(4-methylbenzenesulfonate)(CAS DataBase Reference)
• NIST Chemistry Reference: (4-bromopyridine-2,6-diyl)bis(methylene) bis(4-methylbenzenesulfonate)(221298-01-7)
• EPA Substance Registry System: (4-bromopyridine-2,6-diyl)bis(methylene) bis(4-methylbenzenesulfonate)(221298-01-7)

Safety Data

• Hazardous Substances Data: 221298-01-7(Hazardous Substances Data)

Upstream product

• 499-51-4 Chelidamic acid 
• 112776-83-7 diethyl 4-bromo-2,6-pyridinedicarboxylate 
• 138-60-3 chelidamic acid 
• 162102-79-6 dimethyl 4-bromo-2,6-pyridinedicarboxylate 
• 120491-88-5 4-bromo-2,6-pyridinedimethanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 1950-69-2 toluene-p-sulfonyl bromide 

Downstream Products

• 244610-55-7 dimethyl 5-{5-[3,6,9,12-tetraoxa-18-azabicyclo[12.3.1]octadeca-1⁽¹⁸⁾,14,16-trien-16-yl]-2-thienyl}isophthalate 

Relevant articles and documents

Synthesis and structural studies of 5,12-dioxocyclams capped by 4-substituted pyridines across the amine nitrogens

A series of 4-substituted pyridine-capped 5,12-dioxocyclams was synthesized and fully characterized. The 4-substituent varied from electron-withdrawing groups (NO2, NO, CN) to electron-donating groups (NHCbz, NH2). The most versatile substituent was the 4-bromo group, which could be replaced by a variety of groups using Stille, Sonogashira, or Buchwald-Hartig palladium-catalyzed chemistry. Copper complexes of a majority of these capped dioxocyclams were synthesized and characterized as well.

New advances in the synthesis of tripyridinophane macrocycles suitable to enhance the luminescence of Ln(III) ions in aqueous solution

A series of four new 18-membered hexaaza macrocyclic ligands bearing three endocyclic pyridine units and acetate or methylenephosphonate pendant arms has been prepared. The new synthetic procedure is based on the use of amine and diamine precursors incorporating masked carboxylate or phosphonate functions and on an efficient sodium template effect which controls the crucial macrocyclization step (yields of macrocyclization reactions: 62–88%). This procedure appears as a suitable alternative compared to the classical Richman-Atkins methodology generally used for the preparation of this class of macrocycles. As demonstrated with the EuIII and TbIII complexes derived from two ligands, these tripyridinophane chelators form luminescent and stable mononuclear LnIII complexes in aqueous solution at physiological pH. In such a medium, TbIII complexes exhibit a brightness of 1700 (λexc = 279 nm) and 3000 (λexc = 268 nm) M?1 cm?1.

Synthesis of new enantiopure dimethyl- and diisobutyl -substituted pyridino-18-crown-6 ethers containing a halogen atom or a methoxy group at position 4 of the pyridine ring for enantiomeric recognition studies

New enantiomerically pure dimethyl- and diisobutyl-substituted pyridino-18-crown-6 ethers containing a halogen atom or a methoxy group at position 4 of the pyridine ring [(S,S)-1, (S,S)-2, (S,S)-3, (S,S)-4] have been synthesized. A new synthetic route and

Synthesis and spectroscopic characterisation of fluorescent indicators for Na+ and K+ based on (di)pyridino crown ethers

The synthesis and the spectral and cation binding properties of a fluorescent indicator for Na+, caesium 5-{5-[3,6,9,12-tetraoxa-18-azabicyclo[12.3.1]octadeca-1(18),14,16-trien-16-yl]- 2-thienyl}isophthalate (SPYR), and of two fluorescent indic