221319-66-0

Basic information

• Product Name: (S)-(+)-6-(N,N-dibenzylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester
• CAS NO: 221319-66-0
• Molecular Weight: 424.54
• Mol File: 221319-66-0.mol

Chemical Properties

• CAS DataBase Reference: (S)-(+)-6-(N,N-dibenzylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-6-(N,N-dibenzylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester(221319-66-0)
• EPA Substance Registry System: (S)-(+)-6-(N,N-dibenzylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester(221319-66-0)

Safety Data

• Hazardous Substances Data: 221319-66-0(Hazardous Substances Data)

Upstream product

• 105-36-2 ethyl bromoacetate 
• 221319-62-6 (S)-(+)-N,N-dibenzylamino-2,2-dimethyl-1,3-oxazepan-4-one 
• 137428-35-4 (S)-(+)-(N,N-dibenzoylamino)-4-hydroxy-butanecarboxamide 
• 137428-34-3 (S)-(-)-N,N-dibenzylasparagine benzyl ester 

Downstream Products

• 221319-75-1 (S)-(-)-6-(N-benzyloxycarbonylprolylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester 

Relevant articles and documents

Ex-chiral pool synthesis of aminooxazepinones as conformationally restricted β-amino acid analogs

Starting from natural asparagine, an efficient synthesis of the dibenzyl protected 6-amino-1,3-oxazepin-4-one (7) is reported. According to NMR based conformational studies, the lactam-bridged β-amino acid analog (7) adopts preferentially a twisted boat s