137428-35-4

Upstream product

• 100-52-7 benzaldehyde 
• 128916-04-1 (S)-N,N-dibenzylasparagine 
• 221319-62-6 (S)-(+)-N,N-dibenzylamino-2,2-dimethyl-1,3-oxazepan-4-one 
• 137428-34-3 (S)-(-)-N,N-dibenzylasparagine benzyl ester 

Downstream Products

• 132540-68-2 (S)-3-N,N-dibenzylamino-4-hydroxybutanoic acid methyl ester 
• 137428-36-5 (S)-4-dibenzylamino-γ-butyrolactone 
• 221319-62-6 (S)-(+)-N,N-dibenzylamino-2,2-dimethyl-1,3-oxazepan-4-one 
• 1356108-91-2 (S)-(+)-4-(N,N-dibenzoylamino)pyrrolidin-2-one 
• 36983-58-1 L-Aspol 
• 562104-84-1 (S)-3-Dibenzylamino-4-(4-phenyl-piperazin-1-yl)-butyramide 
• 235425-09-9 ethyl (S)-[4-(N,N-dibenzoylamino)pyrrolidin-2-on-1-yl]acetate 
• 221319-66-0 (S)-(+)-6-(N,N-dibenzylamino)-2,2-dimethyl-1,3-oxazepan-4-on-3-ylacetic acid ethyl ester 

Relevant academic research and scientific papers

Ex-chiral pool synthesis of aminooxazepinones as conformationally restricted β-amino acid analogs

Starting from natural asparagine, an efficient synthesis of the dibenzyl protected 6-amino-1,3-oxazepin-4-one (7) is reported. According to NMR based conformational studies, the lactam-bridged β-amino acid analog (7) adopts preferentially a twisted boat s