22133-40-0

Usage

Uses

Used in Pharmaceutical Industry:
CHEMBRDG-BB 9071293 is used as a potential therapeutic agent for its antioxidant and anti-inflammatory properties, which can contribute to the treatment and management of various diseases and conditions.
Used in Cancer Therapy:
CHEMBRDG-BB 9071293 is used as a potential oncological agent for its ability to inhibit the growth of cancer cells and induce apoptosis, making it a candidate for further research and development in cancer treatment.
Research on CHEMBRDG-BB 9071293 is ongoing to fully understand its potential uses and mechanisms of action in various medical applications, with the aim of harnessing its properties for the development of novel therapeutic strategies.

InChI:InChI=1/C9H13NS/c1-2-7-11-9-5-3-8(10)4-6-9/h3-6H,2,7,10H2,1H3

Upstream product

• 106-94-5 propyl bromide 
• 100-00-5 4-chlorobenzonitrile 
• 1193-02-8 4-aminotiophenol 
• 27826-42-2 p-nitrophenyl n-propyl thiother 

Downstream Products

• 94262-77-8 N-(4-ethoxy-phenyl)-N'-(4-propylsulfanyl-phenyl)-thiourea 
• 22132-22-5 2,2,2-Trichloro-N-(4-propylsulfanyl-phenyl)-acetamide 
• 857489-11-3 4-propylsulfanyl-benzoic acid amide 
• 22683-48-3 4-(propylthio)benzoic acid 
• 189639-08-5 bis(2-chloroethyl)(4-propylthiophenyl)amine 
• 189639-05-2 2-[(2-hydroxy-ethyl)-(4-propylsulfanyl-phenyl)-amino]-ethanol 
• 94438-15-0 N,N'-bis-(4-propylsulfanyl-phenyl)-thiourea 
• 22132-21-4 2-Methyl-N-(4-propylsulfanyl-phenyl)-acrylamide 
• 27978-31-0 chloro-acetic acid-(4-propylsulfanyl-anilide) 
• 855196-51-9 4-(propylthio)benzonitrile 

Relevant academic research and scientific papers

Electrophilic Chlorine from Chlorosulfonium Salts: A Highly Chemoselective Reduction of Sulfoxides

Herein, we describe a selective late-stage deoxygenation of sulfoxides based on a novel application of chlorosulfonium salts and demonstrate a new process using these species generated in situ from sulfoxides as the source of electrophilic chlorine. The use of highly nucleophilic 1,3,5-trimethoxybenzene (TMB) as the reducing agent is described for the first time and applied in the deoxygenation of simple and functionalized sulfoxides. The method is easy to handle, economic, suitable for gram-scale operations, and readily applied for poly-functionalized molecules, as demonstrated with more than 45 examples, including commercial medicines and analogues. We also report the results of competition experiments that define the more reactive sulfoxide and we present a mechanistic proposal based on substrate and product observations.

Sulfoxide-containing aromatic nitrogen mustards as hypoxia-directed bioreductive cytotoxins

A series of diaryl and alkylaryl sulfoxide-containing nitrogen mustards were synthesized and evaluated for their hypoxia-selective cytotoxicity against V-79 cells in vitro as well as for their metabolism profiles with the rat S-9 fractions. In general, th