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221352-49-4

(2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1,2-Pyrrolidinedicarboxylicacid, 5-phenyl-, 1-(1,1-dimethylethyl) ester, (2S,5R)-

    Cas No: 221352-49-4

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  • 1,2-Pyrrolidinedicarboxylicacid, 5-phenyl-, 1-(1,1-dimethylethyl) ester, (2S,5R)-

    Cas No: 221352-49-4

  • USD $ 1.0-1.0 / Metric Ton

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  • 221352-49-4 Structure

  • Basic information

    1. Product Name: (2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID
    2. Synonyms: RARECHEM EM WB 0185;BOC-(2S,5R)-5-PHENYLPYRROLIDINE-2-CARBOXYLIC ACID;(2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID;(2S,5R)-1-(tert-Butoxycarbonyl)-5-phenylpyrrolidine-2-carboxylic acid;Boc-(2S,5R)-5-phenylpyrrolidine-2-carboxylic acid≥ 98% (HPLC)
    3. CAS NO:221352-49-4
    4. Molecular Formula: C16H21NO4
    5. Molecular Weight: 291.34
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 221352-49-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 441.5 °C at 760 mmHg
    3. Flash Point: 220.8 °C
    4. Appearance: /
    5. Density: 1.196 g/cm3
    6. Vapor Pressure: 1.43E-08mmHg at 25°C
    7. Refractive Index: 1.548
    8. Storage Temp.: Store at -15°C
    9. Solubility: N/A
    10. PKA: 3.90±0.40(Predicted)
    11. CAS DataBase Reference: (2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID(CAS DataBase Reference)
    12. NIST Chemistry Reference: (2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID(221352-49-4)
    13. EPA Substance Registry System: (2S,5R)-BOC-5-PHENYL-PYRROLIDINE-2-CARBOXYLIC ACID(221352-49-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 221352-49-4(Hazardous Substances Data)

221352-49-4 Usage

Chemical Properties

White solid

Check Digit Verification of cas no

The CAS Registry Mumber 221352-49-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,1,3,5 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 221352-49:
(8*2)+(7*2)+(6*1)+(5*3)+(4*5)+(3*2)+(2*4)+(1*9)=94
94 % 10 = 4
So 221352-49-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H21NO4/c1-16(2,3)21-15(20)17-12(9-10-13(17)14(18)19)11-7-5-4-6-8-11/h4-8,12-13H,9-10H2,1-3H3,(H,18,19)/t12-,13+/m1/s1

221352-49-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S,5R)-1-[(2-methylpropan-2-yl)oxycarbonyl]-5-phenylpyrrolidine-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:221352-49-4 SDS

221352-49-4Upstream product

221352-49-4Relevant articles and documents

Flexible and modular syntheses of enantiopure 5-cis-substituted prolinamines from l-pyroglutamic acid

Prause, Felix,Kaldun, Johannes,Arensmeyer, Benjamin,Wennemann, Benedikt,Fr?hlich, Benjamin,Scharnagel, Dagmar,Breuning, Matthias

supporting information, p. 575 - 586 (2015/02/19)

A wide range (25 examples) of 5-cis-substituted prolinamines is prepared in five to ten steps starting from cheap l-pyroglutamic acid. Three routes, differing mainly in the order of introduction of the substituents at the 5-cis position, the pyrrolidine nitrogen atom, and the exocyclic amino function, are successfully developed.

VLA-4 inhibitor compounds

-

, (2008/06/13)

Compounds that selectively inhibit the binding of ligands to alpha4beta1 integrin (VLA-4) and methods for their preparation are disclosed. In one embodiment, compounds of the invention are represented by Formula I: As selective inhibitors of VLA-4 mediated cell adhesion, compounds of the present invention are useful in the treatment of conditions associated with such adhesion, including, but not limited to, such conditions as inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis. Also disclosed are pharmaceutical compositions, methods of inhibiting VLA-4 mediated cell adhesion and methods of treating conditions associated with LA-4 mediated cell adhesion, which involve compounds of Formula I.

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