221372-46-9Relevant academic research and scientific papers
Enantiopure building blocks for the synthesis of 3-methyl-2-alkanols. Diastereoselective methylmetal addition to a chiral 2-methylaldehyde followed by lipase catalysed esterification
Larsson, Michael,Andersson, Jimmy,Liu, Rong,Hoegberg, Hans-Erik
, p. 2907 - 2915 (2007/10/03)
The racemic synthetic building block (2R*,3R*)-3-methyl-4- (phenylsulfanyl)butan-2-ol (2R*,3R*)-2 was obtained in a high diastereomeric ratio [95:5, (2R*,3R*)/(2R*,3S*)-ratio] by Lewis acid catalysed dimethylzinc addition to racemic 2-methyl-3- (phenylsul
Total synthesis of brevetoxin A: Part 1: First generation strategy and construction of BCD ring system
Nicolaou,Bunnage, Mark E.,McGarry, Daniel G.,Shi, Shuhao,Somers, Patricia K.,Wallace, Paul A.,Chu, Xin-Jie,Agrios, Konstantinos A.,Gunzner, Janet L.,Yang, Zhen
, p. 599 - 617 (2007/10/03)
Discussed herein is our first generation strategy for the total synthesis of brevetoxin A. This approach relies upon dissection of the molecule at the nine-membered ring site (ring E). A Wittig coupling of requisite polycyclic fragments 3 and 4 followed b
