101212-36-6

Basic information

• Product Name: 1-Propanol, 2-methyl-3-(phenylthio)-, (R)-
• CAS NO: 101212-36-6
• Molecular Formula: C10H14OS
• Molecular Weight: 182.287
• Mol File: 101212-36-6.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 1-Propanol, 2-methyl-3-(phenylthio)-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanol, 2-methyl-3-(phenylthio)-, (R)-(101212-36-6)
• EPA Substance Registry System: 1-Propanol, 2-methyl-3-(phenylthio)-, (R)-(101212-36-6)

Safety Data

• Hazardous Substances Data: 101212-36-6(Hazardous Substances Data)

Usage

Chiral alcohol compound

1-Propanol, 2-methyl-3-(phenylthio)-, (R)is a chiral alcohol compound, meaning it has a central carbon atom with four different groups attached, resulting in different spatial arrangements of the molecule.

Chiral building block

This chemical is commonly used as a chiral building block in organic synthesis.

Precursor in production

It is often used as a precursor in the production of pharmaceuticals, agrochemicals, and fragrances.

Physical properties

1-Propanol, 2-methyl-3-(phenylthio)-, (R)exists as a colorless liquid with a strong odor.

Flammability

This chemical is flammable, so it should be handled with care.

Health hazards

Due to its potential health hazards, appropriate safety precautions should be taken when handling this compound.

Upstream product

• 96947-44-3 (2R)-2-methyl-1-(phenylsulfanyl)-3-(tetrahydropyran-2-yloxy)propane 
• 382150-12-1 (E)-3-phenylthio-2-methylpropen-1-al 
• 51849-22-0 iodomethyl phenyl sulfide 
• 213011-54-2 Acetic acid (R)-2-hydroxymethyl-3-phenylsulfanyl-propyl ester 
• 56102-14-8 2-methyl-3-(phenylsulfanyl)propanal 
• 108-98-5 thiophenol 
• 57432-86-7 3-(phenylthio)propionaldehyde diethyl acetal 
• 27098-65-3 3-phenylsulfanyl-propionaldehyde 
• 882-33-7 diphenyldisulfane 
• 63365-87-7 (+/-)-2-methyl-3-(phenylthio)propan-1-ol 
• 165457-66-9 (R)-2-methyl-3-(phenylsulfanyl)propanoic acid methyl ester 
• 213011-61-1 Acetic acid (S)-3-methanesulfonyloxy-2-phenylsulfanylmethyl-propyl ester 
• 101212-35-5 (4R,5S)-4-Methyl-3-((R)-2-methyl-3-phenylsulfanyl-propionyl)-5-phenyl-oxazolidin-2-one 
• 101212-35-5 (2S,4R,5S)-3-(3-phenylthiomethyl-1-oxopropyl)-5-phenyl-oxazolidin-2-one 

Downstream Products

• 221372-46-9 (R)-2-methyl-3-(phenylsulfanyl)propanal 
• 112995-98-9 (3RS,5R,2'R,3'S,6'S,8'S,10'R)-O-3-(10'-diphenyl-t-butylsiloxy-2',3'-dimethyl-1'7'-dioxaspiro<5.5>undecan-8'-yl)-3,5-dimethyl-6-thiophenylhex-1-enyl S-methyl thiocarbonate 
• 101212-42-4 (1RS,5R,2'R,3'S,6'S,8'S,10'S)-(10'-diphenyl-t-butylsiloxy-2',3'-dimethyl-1',7'-dioxaspiro<5.5>undecan-8'-yl)-3,5-dimethyl-6-thiophenylhex-2-enol 
• 702-00-1 (2-methylallyl)(phenyl)sulfane 
• 101212-46-8 2-{(1E,7E)-(R)-4-Benzenesulfonyl-3-benzoyloxy-9-[(2R,4S,6R,8R,9S)-4-(tert-butyl-diphenyl-silanyloxy)-8,9-dimethyl-1,7-dioxa-spiro[5.5]undec-2-yl]-1,5,7-trimethyl-nona-1,7-dienyl}-4-methoxy-5-methyl-benzoic acid methyl ester 
• 101212-38-8 (4R)-(+)-2,4-dimethyl-1-iodo-5-phenylthiopent-1-ene 
• 101212-37-7 (R)-(+)-2-methyl-3-phenylthiopent-4-yne 
• 101212-45-7 (2R,3S,6S,10R)-(E)-(+)-10-diphenyl-t-butylsiloxy-8<(5'R)-3',5'-dimethyl-6'-phenylsulphonylhex-2'-enyl>-2,3-dimethyl-1,7-dioxaspiro<5.5>undecan 
• 101212-44-6 (2R,3S,6S,10R)-(E)-(+)-10-diphenyl-t-butylsiloxy-8<(5'R)-3',5'-dimethyl-6'thiophenylhex-2'-enyl>-2,3-dimethyl-1,7-dioxaspiro<5.5>undecan 
• 220018-35-9 (E)-(2R,7R)-3-Benzenesulfonyl-1,7-bis-(tert-butyl-dimethyl-silanyloxy)-2,6-dimethyl-non-5-en-4-one 
• 187671-47-2 (1R,2R)-1,2-Dimethyl-3-phenylsulfanylpropyl acetate 
• 220018-34-8 (2R)-3-[1-(tert-butyl)-1,1-dimethylsilyl]oxy-2-methylpropyl phenyl sulfone 
• 934623-87-7 C₂₆H₄₄O₅SiS 
• 934623-85-5 C₃₃H₄₈O₆SiS 

Relevant articles and documents

Diastereoselective sulfa-Michael reactions controlled by a biomass-derived chiral auxiliary

A family of chiral auxiliaries derived from the lignocellulosic biomass pyrolysis product levoglucosenone (LGO) has been screened in the sulfa-Michael reaction. When promoted by inorganic bases with potassium counterions, the auxiliary with geminal benzyl substituents showed diastereoselectivity up to 90:10 for a broad range of α,β-unsaturated esters.

Total synthesis of jerangolid D

A short and convergent synthesis of jerangolid D is described. As key steps, a Blaise reaction is employed to construct the lactone ring, a diastereoselective multicomponent Sakurai condensation leads to the dihydropyran ring, and the skipped diene is ass

Baker's yeast mediated biohydrogenation of sulphur-functionalised methacrolein derivatives. Stereochemical aspects of the reaction and preparation of the two enantiomers of useful C4 bifunctional chiral synthons

The baker's yeast mediated reduction of sulphur-functionalised methacroleins 11, 15 and 18 leads to the preparation of the bifunctional methyl branched C4 chiral synthons 6 and 7. The stereochemical aspects of the biohydrogenation have been investigated. Both the oxidation state of sulphur and the isomeric position of the double bond affected the enantioselectivity of the reduction strongly, thus, offering access to the two enantiomeric forms of 6 and 7.