221372-49-2

Upstream product

• 126694-09-5 (3aR,5S,6aR)-2,2-Dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carboxylic acid methyl ester 
• 126694-08-4 ((R)-2-Methyl-but-3-ene-1-sulfonyl)-benzene 
• 882-33-7 diphenyldisulfane 
• 165457-66-9 (R)-2-methyl-3-(phenylsulfanyl)propanoic acid methyl ester 
• 221372-46-9 (R)-2-methyl-3-(phenylsulfanyl)propanal 

Downstream Products

• 221372-61-8 (3S,5S,6S,8R)-6,8-Bis-benzyloxy-9,9-bis-ethylsulfanyl-3,5-dimethyl-non-1-en-5-ol 
• 126694-12-0 1-[(2S,3R,5S,6R)-3,5-Bis-benzyloxy-6-methyl-6-((S)-2-methyl-but-3-enyl)-tetrahydro-pyran-2-yl]-propan-2-one 
• 221372-65-2 (3R,5S,6R)-3,5-Bis-benzyloxy-6-methyl-6-((S)-2-methyl-but-3-enyl)-tetrahydro-pyran-2-ol 
• 221464-83-1 (S)-5-{(2R,3S,5R,6S)-3,5-Bis-benzyloxy-6-[3-benzyloxycarbonyl-2-(tert-butyl-dimethyl-silanyloxy)-2-methyl-propyl]-2-methyl-tetrahydro-pyran-2-yl}-3-(tert-butyl-dimethyl-silanyloxy)-4-methyl-pentanoic acid benzyl ester 
• 126694-06-2 (2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-2,11-Bis-(2-benzyloxy-ethyl)-10-(tert-butyl-diphenyl-silanyloxy)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cycloocten-3-ol 
• 126694-03-9 (Z)-(4S,5aS,6aR,8R,12aS,13aR)-2,11-Bis-(2-benzyloxy-ethyl)-4,6a,8-trimethyl-4,5,5a,6a,7,8,9,12a,13,13a-decahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cyclooctene 
• 126694-04-0 (2S,3R,4S,5aS,6aR,8R,10S,11R,12aS,13aR)-2,11-Bis-(2-benzyloxy-ethyl)-4,6a,8-trimethyl-tetradecahydro-1,6,12-trioxa-cyclohepta[4,5]benzo[1,2]cyclooctene-3,10-diol 
• 126693-95-6 (S)-3-[(2R,3S,5R,6S)-3,5-Bis-benzyloxy-2-methyl-6-(2-oxo-propyl)-tetrahydro-pyran-2-yl]-2-methyl-propionaldehyde 

Relevant academic research and scientific papers

Total synthesis of brevetoxin A: Part 1: First generation strategy and construction of BCD ring system

Discussed herein is our first generation strategy for the total synthesis of brevetoxin A. This approach relies upon dissection of the molecule at the nine-membered ring site (ring E). A Wittig coupling of requisite polycyclic fragments 3 and 4 followed b