221380-88-7

Basic information

• Product Name: [(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-acetaldehyde
• Synonyms: [(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-acetaldehyde
• CAS NO: 221380-88-7
• Molecular Weight: 632.988
• Mol File: 221380-88-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: [(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-acetaldehyde(221380-88-7)
• EPA Substance Registry System: [(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-acetaldehyde(221380-88-7)

Safety Data

• Hazardous Substances Data: 221380-88-7(Hazardous Substances Data)

Upstream product

• 994-30-9 triethylsilyl chloride 
• 122821-83-4 2,6-Anhydro-4-O-benzyl-1-O-(tert-butyldiphenylsilyl)-3,7,8,9-tetradeoxy-D-altro-non-8-enitol 
• 122821-82-3 2,6-Anhydro-1-O-(tert-butyldiphenylsilyl)-3,7,8,9-tetradeoxy-4,5-O-isopropylidene-D-altro-non-8-enitol 
• 122821-81-2 2,6-Anhydro-1-O-(tert-butyldiphenylsilyl)-3,7,8,9-tetradeoxy-4,5-O-isopropylidene-D-altro-non-8-enitol 
• 100-39-0 benzyl bromide 
• 155434-13-2 (2R,3S,4S,6S)-2-Allyl-4-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran 

Downstream Products

• 155434-15-4 (E)-4-[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-yl]-2-methyl-but-2-en-1-ol 
• 155434-33-6 (E)-3-[(2S,4S,4aR,5aR,8S,9R,10aS,11aR)-8-Acetoxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-5a-methyl-4-triisopropylsilanyloxy-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-9-yl]-acrylic acid methyl ester 
• 155434-35-8 (2S,4S,4aR,5aR,8S,9R,10aS,11aR)-9-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-2-(tert-butyl-diphenyl-silanyloxymethyl)-5a-methyl-4-triisopropylsilanyloxy-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8-ol 
• 155434-25-6 3-[(2R,3S,4aR,6S,8S,8aR)-3-Acetoxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-8-triisopropylsilanyloxy-octahydro-pyrano[3,2-b]pyran-2-yl]-propionic acid methyl ester 
• 155434-36-9 3-[(2S,4S,4aR,5aR,8S,9R,10aS,11aR)-8-Allyloxy-2-(tert-butyl-diphenyl-silanyloxymethyl)-5a-methyl-4-triisopropylsilanyloxy-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-9-yl]-propan-1-ol 
• 155434-21-2 Acetic acid (2S,4S,4aR,5aR,8S,9R,10aS,11aR)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5a-methyl-4-triisopropylsilanyloxy-9-vinyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8-yl ester 
• 155434-12-1 (E)-3-[(2R,3S,4aR,6S,8S,8aS)-3-Acetoxy-8-benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-octahydro-pyrano[3,2-b]pyran-2-yl]-acrylic acid methyl ester 
• 155434-27-8 (2R,3S,4aR,6S,8S,8aR)-2-[3-(tert-Butyl-dimethyl-silanyloxy)-propyl]-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-8-triisopropylsilanyloxy-octahydro-pyrano[3,2-b]pyran-3-ol 
• 161980-26-3 (2R,3S)-3-[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-ylmethyl]-2-methyl-oxirane-2-carbaldehyde 
• 155434-34-7 (2S,4S,4aR,5aR,8S,9R,10aS,11aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-9-(3-hydroxy-propyl)-5a-methyl-4-triisopropylsilanyloxy-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8-ol 
• 155434-16-5 {(2S,3S)-3-[(2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-3-triethylsilanyloxy-tetrahydro-pyran-2-ylmethyl]-2-methyl-oxiranyl}-methanol 
• 155434-17-6 (2R,3S,4S,6S)-4-Benzyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-((2S,3S)-3-methyl-3-vinyl-oxiranylmethyl)-3-triethylsilanyloxy-tetrahydro-pyran 
• 155434-31-4 (2S,4S,4aR,5aR,8S,9R,10aS,11aR)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-5a-methyl-4-triisopropylsilanyloxy-9-vinyl-dodecahydro-1,5,10-trioxa-cyclohepta[b]naphthalen-8-ol 
• 155434-28-9 3-[(2R,3S,4aR,6S,8S,8aR)-3-Allyloxy-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-8-triisopropylsilanyloxy-octahydro-pyrano[3,2-b]pyran-2-yl]-propan-1-ol 

Relevant articles and documents

Total synthesis of brevetoxin A: Part 3: Construction of GHIJ and BCDE ring systems

Successful syntheses of highly complex intermediates 2 (GHIJ ring system) and 3 (BCDE ring system) for the total synthesis of brevetoxin A (1) are described. Several of our methodologies were utilized to achieve this goal: i) hydroxy epoxide cyclizations

Stereocontrolled Synthesis of the Hemibrevetoxin Ring System via an Allylic Tin Method

Stereocontrolled synthesis of the 7,7,6,6-tetracyclic ether skeleton of the hemibrevetoxin skeleton has been accomplished via the intramolecular allylic tin-aldehyde and ketone) condensation.