2215-76-1

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-Formylphenoxy)benzaldehyde 96 is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4-(4-Formylphenoxy)benzaldehyde 96 is employed as a precursor for the production of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection, thereby supporting agricultural productivity.
Used in Organic Synthesis:
4-(4-Formylphenoxy)benzaldehyde 96 is used as a building block in organic synthesis for the creation of a wide range of fine chemicals. Its versatility in chemical reactions enables the production of specialty chemicals used in various industries, including fragrances, dyes, and coatings.
Used as a Reagent:
4-(4-FORMYLPHENOXY)BENZALDEHYDE 96 also serves as a reagent in the preparation of other organic compounds. Its reactivity and functional groups make it a valuable tool in the synthesis of complex organic molecules, facilitating research and development in the field of organic chemistry.

Upstream product

• 6508-04-9 4-(4'-cyanophenoxy)benzonitrile 
• 7158-32-9 4,4'-bis(chlorocarbonyl)diphenyl oxide 
• 1579-40-4 1,1'-oxybis(4-methyl-benzene) 
• 2215-89-6 oxybis(benzoic acid) 
• 555-16-8 4-nitrobenzaldehdye 
• 123-08-0 4-hydroxy-benzaldehyde 
• 99-96-7 4-hydroxy-benzoic acid 
• 3096-86-4 4,4'-oxybis(ethyl benzoate) 
• 2350-43-8 4,4'-oxy-bis(4,1-phenylene) dimethanol 
• 586-76-5 4-Bromobenzoic acid 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 120-47-8 Ethyl 4-hydroxybenzoate 
• 2050-47-7 4,4'-dibromodiphenyl ether 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 103800-72-2 2,2'-diphenyl-4H,4'H-4,4'-(4,4'-oxy-di-benzylidene)-bis-oxazol-5-one 
• 23484-24-4 4,4'-oxy-di-benzaldehyde bis-carbamimidoylhydrazone 
• 27363-28-6 4,4'-oxy-di-benzaldehyde bis-phenylimine 
• 2509-22-0 (1-p-hydorxy-cis-cinnamoyl)cinnamic acid 
• 2215-89-6 oxybis(benzoic acid) 
• 90178-69-1 4,4'-Bis(4-cyan-2-nitrostyryl)diphenylether 
• 3731-93-9 4,4'-Bis-(4-hydroxy-phenyliminomethyl)-diphenylaether 
• 3525-69-7 4,4'-Bis-cyclohexyliminomethyl-diphenylaether 
• 3525-58-4 4,4'-Bis-(4-methoxy-phenyliminomethyl)-diphenylaether 
• 3906-51-2 4,4'-Bis-(4-carboxy-phenyliminomethyl)-diphenylether 
• 3782-58-9 4,4'-Bis-(4-ethoxycarbonyl-phenyliminomethyl)-diphenylether 
• 7158-32-9 4,4'-bis(chlorocarbonyl)diphenyl oxide 
• 1266348-22-4 (2E,2'E)-3,3'-(4,4'-oxybis(4,1-phenylene))-bis(1-(2-hydroxy-4,6-dimethoxyphenyl)prop-2-en-1-one) 
• 3806-08-4 4.4'-Bis-(3-hydroxy-4-methoxycarbonyl-phenyliminomethyl)-diphenylaether 

Relevant academic research and scientific papers

Bis-Benzyl-Tetrahydroisoquinoline Derivatives As Therapeutics For Filovirus

Bis-benzyl-tetrahydroisoquinoline analogs that are derivatives of the cyclic products tetrandrine (TETN) and cepharanthine (CEPH). The analogs indicate activity against filovirus infections, including the type species Marburg virus (MARV) and Ebola virus (EBOV).

Preparation method of 4-(4-formyl phenoxy)benzaldehyde

The invention relates to the technical field of chemical synthesis, in particular to a preparation method of 4-(4-formyl phenoxy)benzaldehyde. The preparation method comprises the steps that 4-hydroxybenzaldehyde and potassium carbonate are adopted for re

Styrene-based compound and preparation method and application thereof

The invention discloses a styrene-based compound, which is at least a 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound of the following structural formula. The invention also discloses a preparation method and application of the 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound of the structural formula. The 5-(4-(4-(3,5-dyhydroxystyryl)phenoxyl)styryl)-1,3-benzenediol compound disclosed by the invention is used for inhibiting the abnormal growth of B-cells by lowering AKT/mTOR signal conduction. The formula is shown in the specification.

Palladium-on-Carbon-Catalyzed Coupling of Nitroarenes with Phenol: Biaryl Ether Synthesis and Evidence of an Oxidative-Addition-Promoted Mechanism

Nucleophilic substitution in nitroarenes to form biaryl ethers is of fundamental importance in organic synthesis. Under non-catalytic conditions, this can occur if highly activated nitroarenes are used or if the nucleophile is activated by a strong stoichiometric base. We established a new method involving the use of a ligand-free palladium-on-carbon (Pd/C) catalyst for the cross-coupling of activated nitroarenes with relatively non-nucleophilic phenol derivatives, including naphthol, in the absence of harsh bases. Control experiments, hot filtration, the three-phase test, and inductively coupled plasma atomic emission spectroscopy analysis revealed that the catalysis proceeded through an usual oxidative addition step of the nitroarene to Pd/C, which resulted in the release of active palladium particles having extremely high catalytic activity. DFT calculations revealed the origin of the selectivity of the activated nitroarenes.

Highly efficient heterogeneous copper-catalysed O-arylation of phenols by nitroarenes leading to diaryl ethers

The heterogeneous O-arylation of phenols by nitroarenes was achieved in DMF at 100 °C by using an MCM-41-immobilised bidentate nitrogen copper(II) complex [MCM-41-2N-Cu(OAc)2] as catalyst, yielding a variety of unsymmetrical diaryl ethers in good to excellent yields. This heterogeneous copper catalyst can be easily prepared by a simple procedure from commercially readily available and inexpensive reagents, recovered by filtration of the reaction solution and recycled at least seven times without significant loss of activity.

Novel PTP1B enzyme inhibitor, preparation method and applications thereof

The present invention provides a novel PTP1B enzyme inhibitor, a preparation method and applications thereof, and particularly discloses a class of bis 2-substituted ethylene sulfonate compounds and a preparation method thereof, and uses of the bis 2-substituted ethylene sulfonate compounds as the PTP1B enzyme activity inhibitor. According to the present invention, the prepared novel compound has good PTP1B enzyme activity inhibition effect, and has the application value in preparation of drugs for treatment and prevention of diabetes and obesity.

Y-shaped bis-arylethenesulfonic acid esters: Potential potent and membrane permeable protein tyrosine phosphatase 1B inhibitors

Known PTP1B inhibitors with bis-anionic moieties exhibit potent inhibitory activity, good selectivity, however, they are incapable of penetrating cellular membranes. Based upon our finding of a new pharmacophoric group in inhibition of PTP1B and the struc

Tetrakisphenol compd., photosensitive agent, and photosensitive resin composition, the cured film, using the same, and a protective film, the insulating film, a semiconductor device, and display device

PROBLEM TO BE SOLVED: To provide a new tetrakisphenol compound usable for a positive photosensitive resin having good storage stability and satisfying both of exposure sensitivity and resolution. SOLUTION: There is provided a tetrakisphenol compound represented by general formula (1). (In the formula, Ar is aryl having phenolic hydroxy, may be the same or different and is substituted at one of the second, third, forth, fifth and sixth sites). COPYRIGHT: (C)2012,JPOandINPIT

Synthesis and characterization of novel unnatural bichalcones

Five bichalcones (5-1 ～ 5-4, 9) were prepared by the reaction of biphenyl-4,4′-dicarbaldehyde (4) and 4,4′-dioxybenzaldehyde (8) with the respective acetophenone analogs via Claisen-Schmidt condensation and were then fully identified by 1H-NMR, 13C-NMR and mass analyses.

Tuning the size of macrocyclic cavities in trianglimine macrocycles

The synthesis of aromatic dicarboxaldehydes is described along with their reactivity in the [3 + 3] cyclocondensation reaction with (1R,2A)- diaminocyclohexane to give trianglimine macrocycles. In particular, the scope and limitation of the reaction with regard to complete control of the cavity size of the macrocycles is discussed producing a total of 11 macrocycles with different cavity sizes ranging from 9 to 23 A. The Royal Society of Chemistry 2005.