221526-71-2Relevant academic research and scientific papers
Practical synthesis of a 3, 4, 4a, 5, 8, 8a-hexahydro-2H-isoquinoline-1, 6-dione ring system by the Diels-Alder reaction of an optically active dienophile, a 5, 6-dihydro-1H-pyridin-2-one derivative, with siloxydiene
Nakagawa, Masako,Uchida, Hideharu,Ono, Koji,Kimura, Yoshiyuki,Yamabe, Mariko,Watanabe, Takeshi,Tsuji, Riichiro,Akiba, Masakatsu,Terada, Yukiyoshi,Nagaki, Dai,Ban, Sachiko,Miyashita, Naoki,Kano, Takuya,Theeraladanon, Chumpol,Hatakeyama, Keisuke,Arisawa, Mitsuhiro,Nishida, Atsushi
, p. 721 - 733 (2007/10/03)
An efficient method for preparing chiral 3-substituted-5, 6-dihydro-1H-pyridin-2-one (1) in large scale, based on a modification of our previous method, is described. The large scale Diels-Alder reaction of 1 with siloxydiene (2) to synthesize hexahydrois
An efficient access to the optically active manzamine tetracyclic ring system
Uchida, Hideharu,Nishida, Atsushi,Nakagawa, Masako
, p. 113 - 116 (2007/10/03)
The highly stereoselective synthesis of the optically active tetracyclic core 2 of Manzamine A 1 was achieved via the Diels-Alder reaction of dihydropyridinone 12b, derived from L-serine, with siloxydienes, followed by sequential new and conventional pathways.
