22165-36-2Relevant articles and documents
New antipsychotic agents with serotonin and dopamine antagonist properties based on a pyrrolo[2,1-b][1,3]benzothiazepine structure
Campiani, Giuseppe,Nacci, Vito,Bechelli, Susanna,Ciani, Silvia M.,Garofalo, Antonio,Fiorini, Isabella,Wikstr?m, H?kan,De Boer, Peter,Liao, Yi,Tepper, Pieter G.,Cagnotto, Alfredo,Mennini, Tiziana
, p. 3763 - 3772 (2007/10/03)
The development of a synthetic approach to the novel pyrrolo[2,1- b][1,3]benzothiazepine and its derivatives and their biological evaluation as potential antipsychotic drugs are described. In binding studies these compounds proved to be potent 5-HT2