22184-85-6

Basic information

• Product Name: Benzenesulfonamide, 4-iodo-N,N-dimethyl-
• Synonyms: Benzenesulfonamide, 4-iodo-N,N-dimethyl-;4-iodo-N,N-dimethylbenzenesulfonamide
• CAS NO: 22184-85-6
• Molecular Formula: C₈H₁₀INO₂S
• Molecular Weight: 311
• Mol File: 22184-85-6.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenesulfonamide, 4-iodo-N,N-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-iodo-N,N-dimethyl-(22184-85-6)
• EPA Substance Registry System: Benzenesulfonamide, 4-iodo-N,N-dimethyl-(22184-85-6)

Safety Data

• Hazardous Substances Data: 22184-85-6(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 1709-59-7 4-amino-N,N-dimethylbenzenesulphonamide 
• 5122-99-6 4-iodophenylboronic acid 
• 98-61-3 p-Iodobenzenesulfonyl chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 14417-01-7 N,N-dimethylbenzenesulfonamide 

Relevant articles and documents

A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions

A general electrochemical system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an alcohol as a co-solvent.

Using Anilines as Masked Cross-Coupling Partners: Design of a Telescoped Three-Step Flow Diazotization, Iododediazotization, Cross-Coupling Process

The conversion of commercially available anilines into biaryl and biarylacetylene products was realized by using a telescoped, three-reactor flow diazotization/iododediazotization/cross-coupling process. The segmented flow stream created by off-gassing during the Sandmeyer sequence was restored to a continuous column of reaction solution by using a specially designed continuous-flow unit controlled by custom software created in-house. The resultant aryl iodide was then combined with a stream of cross-coupling solution that fed into the final reactor. The system proved versatile as modifications to the diazotization/iododediazotization sequence could be made rapidly to account for any substrate specificity (e.g., solubility problems), leading to a wide substrate scope of Suzuki–Miyaura and Sonogashira cross-coupled products.

COMPOUNDS WHICH POTENTIATE AMPA RECEPTOR AND USES THEREOF IN MEDICINE

Compounds of formula (I) and salts and solvates are provided: formula (I). Processes for preparation, pharmaceutical compositions, and uses thereof as a medicament, for example in the treatment of a disease or condition mediated by a reduction or imbalance in glutamate receptor function, such as schizophrenia or cognition impairment, are also disclosed.