22187-89-9

Upstream product

• 104869-92-3 5-Benzenesulfonyl-4-oxo-6-phenyl-hexanoic acid methyl ester 
• 104-53-0 3-phenyl-propionaldehyde 
• 292638-85-8 acrylic acid methyl ester 
• 37904-38-4 5-phenylpent-1-en-3-ol 
• 645-45-4 hydrocinnamic acid chloride 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 67-56-1 methanol 
• 13122-67-3 6-phenyl-4-oxohexanoic acid 
• 103681-39-6 Se-methyl selenohydrocinnamate 

Downstream Products

• 112607-22-4 (+)-(R)-5-(2-phenylethyl)dihydrofuran-2(3H)-one 

Relevant academic research and scientific papers

DESULFONYLATION OF β-KETO SULFONES WITH THE HANTZSCH ESTER, AN NAD(P)H MODEL

Carbon-sulfur bonds in β-keto sulfones were reduced smoothly to carbon-hydrogen bonds with the Hantzsch ester, a model of NAD(P)H.

Cross metathesis of allyl alcohols: How to suppress and how to promote double bond isomerization

Under standard conditions the cross metathesis of allyl alcohols and methyl acrylate is accompanied by the formation of ketones, resulting from uncontrolled and undesired double bond isomerization. By conducting the CM in the presence of phenol, the catalyst loading and the reaction time required for quantiative conversion can be reduced, and isomerization can be suppressed. On the other hand, consecutive isomerization can be deliberately promoted by evaporating excess methyl acrylate after completing cross metathesis and by adding a base or silane as chemical triggers.

Direct intermolecular hydroacylation of N,N-dialkylacrylamides with aldehydes catalyzed by a cationic rhodium(I)/dppb complex

Figure presented A cationic rhodium(l)/dppb complex catalyzed direct intermolecular hydroacylation of N,N-dialkylacrylamides with both aliphatic and aromatic aldehydes has been achieved through the stabilization of acylrhodium intermediates by alkene chel

NAD(P)+-NAD(P)H Models. 65. Photochemical Reductive Desulfonylation of β-Keto Sulfones with Hantzsch Ester

A new procedure for the reductive desulfonylation of β-keto sulfones is described.The reaction proceeds under a photochemical conditions with the Hantzsch ester in pyridine in the presence of ruthenium(II).Various functional groups are unaffected under the reaction conditions.Application of the procedure to the syntheses of certain natural products is also described.