2219-73-0

Usage

Uses

Used in Perfumery and Cosmetics Industry:
4-Ethyl-o-cresol is used as a fragrance ingredient for its strong odor, contributing to the scent profiles of various perfumes and cosmetics.
Used in Soap and Detergent Industry:
In the soap and detergent industry, 4-ethyl-o-cresol is used as a flavoring agent to impart specific scents to these products, enhancing their appeal to consumers.
Used in Food and Beverage Industry:
4-Ethyl-o-cresol is utilized as a flavoring agent in the food and beverage industry to add unique taste and aroma to products, improving their sensory qualities.
Used in Personal Care Products:
Due to its antimicrobial properties, 4-ethyl-o-cresol is used as an ingredient in personal care products to help maintain hygiene and prevent microbial growth.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-ethyl-o-cresol is used for its antimicrobial properties, often incorporated into formulations to ensure the sterility and safety of medications.

InChI:InChI=1/C9H12O/c1-3-8-4-5-9(10)7(2)6-8/h4-6,10H,3H2,1-2H3

Upstream product

• 876-02-8 4-hydroxy-3-methylphenyl methyl ketone 
• 75-07-0 acetaldehyde 
• 95-48-7 ortho-cresol 
• 78043-60-4 4-ethyl-1-methyl-4-nitrocyclohexa-2,5-dienyl acetate 
• 64-17-5 ethanol 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 17096-14-9 1,1-bis-(3-methyl-4-hydroxyphenyl)ethane 

Downstream Products

• 115322-98-0 2,6-bis-(5-ethyl-2-hydroxy-3-methyl-benzyl)-3,5-dimethyl-phenol 
• 116530-88-2 4-ethyl-2-methyl-cyclohexanol 
• 104216-48-0 (4-ethyl-2-methyl-phenoxy)-acetic acid 
• 26052-86-8 4-ethyl-2-tert-butyl-6-methyl-phenol 
• 21573-35-3 4-ethyl-2-methylphenyl methyl ether 
• 18606-50-3 1-(3-tert-butyl-4-hydroxy-5-methyl-phenyl)-ethanone 
• 56520-99-1 4-ethyl-2-methyl-6-nitrophenol 

Relevant academic research and scientific papers

Selective hydrodeoxygenation of hydroxyacetophenones to ethyl-substituted phenol derivatives using a FeRu?SILP catalyst

The selective hydrodeoxygenation of hydroxyacetophenone derivatives is achieved opening a versatile pathway for the production of valuable substituted ethylphenols from readily available substrates. Bimetallic iron ruthenium nanoparticles immobilized on an imidazolium-based supported ionic liquid phase (Fe25Ru75?SILP) show high activity and stability for a broad range of substrates without acidic co-catalysts. This journal is

The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part III: The three microdose candidates

In this manuscript, we report the discovery of the substituted 2-trifluoromethyl-2H-benzopyran-3-carboxylic acids as a novel series of potent and selective cyclooxygenase-2 (COX-2) inhibitors. We provide the structure-activity relationships, optimization of design, testing criteria, and human half-life data. The challenge of a surprisingly long half-life (t 1/2 = 360 h) of the first clinical candidate 1 and human t 1/2 had been difficult to predict based on allometric scaling for this class of highly ppb compounds. We used a microdose strategy which led to the discovery of clinical agents 18c-(S), 29b-(S), and 34b-(S) with human half-life of 57, 13, and 11 h.

Carboxylic Acid Compounds and Use Thereof

Provision of a superior URAT1 activity inhibitor effective for the treatment and the like of a pathology involving uric acid, such as hyperuricemia, gouty tophus, acute gouty arthritis, chronic gouty arthritis, gouty kidney, urinary lithiasis, renal dysfunction, coronary heart disease, ischemic cardiac diseases and the like. A URAT1 activity inhibitor containing a compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, or a solvate thereof as an active ingredient: [image] wherein each symbol is as defined in the specification.

BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (1). Wherein Z, X, R1, R2, R3, and R4 are as described in specification.

CHROMENE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS

The subject invention concerns methods and compounds that have utility in the treatment of a condition associated with cyclooxygenase-2 mediated disorders. Compounds of particular interest are benzopyrans and their analogs defined by formula (I). Wherein Z, X, R1, R2, R3, and R4 are as described in the specification.

Catalytic ethylation of phenols

Alkylation of phenol and cresols with ethanol in the presence of iron-aluminum catalyst was studied.

Polycyclic phenols, alcohols and ketones from phenols, cyclic alcohols and cyclic ketones using a nickel oxide/manganese oxide/magnesium oxide catalyst in presence of at least one of hydrogen and nitrogen

At least one of a polycyclic phenol, a polycyclic alcohol and a polycyclic ketone is produced under hydrogenation conditions using a nickel oxide/manganese oxide/magnesium oxide catalyst by subjecting at least one of a monocyclic ketone, a monocyclic alcohol and a monocyclic phenol to said conditions and said catalyst.

Conversion of alkyl and aryl hydroxy compounds producing aldehyde, alcohol and ketone using manganese oxide/nickel oxide/magnesium oxide catalysts

Alkyl and aryl hydroxy compounds are converted to aldehydes, alcohols, and ketones in the presence of hydrogen using a catalyst comprised of the oxides of manganese, nickel and magnesium.

ipso Nitration. XXIII. Reactions of cyclohexadiene adducts from nitration of 4-ethyltoluene in acetic anhydride

The diastereoisomers of 4-ethyl-1-methyl-4-nitrocyclohexa-2,5-dienyl acetate (1) and 1-ethyl-4-methyl-4-nitrocyclohexa-2,5-dienyl acetate (2) are stereospecifically reduced to the corresponding nitrocyclohexadienols with aluminum hydride.Each dienol is stereospecifically methylated to the corresponding methyl ether with methyl iodide, silver oxide, and potassium hydroxide.Acid-catalysed solvolysis of the acetates 1 and 2 results in the substitution of the acetate moiety by other nucleophiles and these reactions are not stereospecific.The products of rearomatization of dienyl acetates, dienols and dienyl methyl ethers depend on the acidity and ionizing power of the solvents and are readily explained in terms of reactions involving a nitrocyclohexadienyl cation or acetoxy- (hydroxy-, methoxy-)cyclohexadienyl cation as key intermediates.In the 4-acetoxy-4-alkylcyclohexadienyl cation 1,2-migration of the acetoxyl group is more rapid then alkyl migration, but 1,2-alkyl migration is faster then migration of the hydroxyl or methoxyl groups in the corresponding cations. 1-Ethyl-4-methoxy-4-methylcyclohexa-2,5-dien-1-ol and 4-ethyl-3-nitrotoluene are significant minor products in the solvolysis of 1-ethyl-4-methyl-4-nitrocyclohexa-2,5-dien-1-ol in aqueous methanol.Nitration of p-ethyltoluene in the presence of sulfuric acid or in trifluoracetic anhydride gives a mixture of 4-ethyl-2-nitro- and 4-ethyl-3-nitrotoluene in a 2:1 ratio.