22190-40-5 Usage
Description
1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline is an organic heterocyclic compound with the chemical formula C12H13BrNO. It features a quinoline core and a bromine substituent at the 6-position, along with an acetyl group at the 1-position, which imparts a distinct odor and flavor. 1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline holds potential in pharmaceutical and medicinal chemistry due to its quinoline scaffold, commonly found in various bioactive molecules. Its synthesis and properties are of interest to researchers in organic chemistry, and it may be developed further as a drug candidate or a chemical building block in organic synthesis.
Uses
Used in Pharmaceutical and Medicinal Chemistry:
1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline is used as a chemical building block for the development of new pharmaceuticals and medicinal agents. Its quinoline scaffold is a key structural element in many bioactive compounds, making it a promising candidate for the creation of novel drugs with potential therapeutic applications.
Used in Organic Chemistry Research:
1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline serves as a subject of study for researchers in the field of organic chemistry. Its synthesis and properties are of interest for understanding the behavior of heterocyclic compounds and for exploring new methods of synthesis that could lead to the discovery of additional related compounds with useful properties.
Used in Drug Development:
As a potential drug candidate, 1-acetyl-6-bromo-1,2,3,4-tetrahydroquinoline may be utilized in the development of new therapeutic agents. Its unique structure and the presence of the quinoline core suggest that it could have biological activity, making it a candidate for further investigation and optimization to treat various diseases or conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 22190-40-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,9 and 0 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 22190-40:
(7*2)+(6*2)+(5*1)+(4*9)+(3*0)+(2*4)+(1*0)=75
75 % 10 = 5
So 22190-40-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H12BrNO/c1-8(14)13-6-2-3-9-7-10(12)4-5-11(9)13/h4-5,7H,2-3,6H2,1H3
22190-40-5Relevant articles and documents
CANCER TREATMENTS TARGETING CANCER STEM CELLS
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Paragraph 0331; 0362; 0364, (2019/11/19)
Disclosed are compounds, methods, compositions, and kits that allow for treating cancer by, e.g., targeting cancer stem cells. In some embodiments, the cancer is colorectal cancer, gastric cancer, gastrointestinal stromal tumor, ovarian cancer, lung cancer, breast cancer, pancreatic cancer, prostate cancer, testicular cancer, or lymphoma. In some embodiments, the cancer is liver cancer, endometrial cancer, leukemia, or multiple myeloma. The compounds utilized in the disclosure are of Formula (0), (O'), and (I):
THERAPEUTIC COMPOUNDS AND USES THEREOF
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, (2017/12/29)
The present invention relates to compounds of formula (I) and formula (II): and to salts thereof, wherein R1-R4 of formula (I) and R5-R6 of formula (II) have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of CBP and/or EP300. Also included are pharmaceutical compositions comprising a compound of formula (I) of formula (II), or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various CBP and/or EP300-mediated disorders.
N-THIAZOL-2-YL-BENZAMIDE DERIVATIVES
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Page/Page column 31, (2008/06/13)
The invention relates to N-thiazol-2-yl-benzamide derivatives of the formula I in the description wherein the variables are as defined in the claims. The compounds are A2A-receptor ligands, such as antagonists, agonists, reverse agonists or partial agonists, and are useful in the treatment of neurological and psychiatric disorders where an A2A-receptor is implicated.
