221910-02-7

Basic information

• Product Name: 2-Propyn-1-one, 3-(2-aminophenyl)-1-(4-chlorophenyl)-
• CAS NO: 221910-02-7
• Molecular Formula: C15H10ClNO
• Molecular Weight: 255.703
• Mol File: 221910-02-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Propyn-1-one, 3-(2-aminophenyl)-1-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propyn-1-one, 3-(2-aminophenyl)-1-(4-chlorophenyl)-(221910-02-7)
• EPA Substance Registry System: 2-Propyn-1-one, 3-(2-aminophenyl)-1-(4-chlorophenyl)-(221910-02-7)

Safety Data

• Hazardous Substances Data: 221910-02-7(Hazardous Substances Data)

Upstream product

• 637-87-6 1-Chloro-4-iodobenzene 
• 201230-82-2 carbon monoxide 
• 103529-16-4 2-[(trimethylsilyl)ethynyl]aniline 
• 122-01-0 4-chloro-benzoyl chloride 
• 199454-06-3 (2-ethynylphenyl)carbamic acid 1,1-dimethylethyl ester 
• 52670-38-9 2-ethynylaniline 
• 615-43-0 2-iodophenylamine 

Downstream Products

• 1149749-67-6 C₂₅H₁₉ClN₂O 
• 1149749-68-7 C₂₃H₁₇ClN₂O₂ 
• 1149749-65-4 C₂₄H₁₉ClN₂O 
• 1149749-66-5 C₂₁H₁₅ClN₂O₂ 
• 78396-10-8 2-(4’-chlorophenyl)-4-quinolone 
• 1026-22-8 (4-chlorophenyl)(1H-indol-2-yl)methanone 
• 1035989-44-6 1-{3-[2-(4-chlorophenyl)quinolin-4-yl]phenyl}ethanone 

Relevant articles and documents

TBAF-Catalyzed Tandem Synthesis of Triazolo[4,5-c]quinolines at Ambient Temperature

A mild, efficient and metal-free synthetic method for 1H-[1,2,3]triazolo[4,5-c]quinolines has been developed via intermolecular [3+2] cycloaddition of β-(2-aminoaryl)-α,β-ynones and TMS-N3, followed by intramolecular dehydration annulation sequential reactions. With 5 mmol-% of TBAF as catalyst, the reaction can smoothly proceed in DMF at ambient temperature to afford a wide range of functionalized 1H-[1,2,3]triazolo[4,5-c]quinolines in good to excellent yields.

The palladium-catalyzed transfer hydrogenation/heterocyclization of β- (2-aminophenyl)-α,β-ynones. An approach to 2-aryl- and 2-vinylquinolines

The palladium-catalyzed transfer hydrogenation/cyclization of readily available β-(o-aminophenyl)-α,β-ynones I affords 2-aryl- and 2- vinylquinolines 3 in good yield.