222022-89-1

Basic information

• Product Name: 2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol
• Synonyms: 2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol
• CAS NO: 222022-89-1
• Molecular Weight: 262.392
• Mol File: 222022-89-1.mol

Chemical Properties

• CAS DataBase Reference: 2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol(222022-89-1)
• EPA Substance Registry System: 2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol(222022-89-1)

Safety Data

• Hazardous Substances Data: 222022-89-1(Hazardous Substances Data)

Upstream product

• 222022-94-8 (1'S)-2-benzyloxy-4-methyl-6-(1',2',2'-trimethylcyclopentyl)phenol 
• 222022-92-6 (1'S)-3,4-dimethoxy-5-(1',2',2'-trimethylcyclopentyl)benzyl alcohol 
• 222022-91-5 (1'S)-3,4-Dimethoxy-5-(1',2',2'-trimethylcyclopentyl)benzaldehyde 
• 222022-93-7 (1'S)-1,2-dimethoxy-5-methyl-3-(1',2',2'-trimethylcyclopentyl)benzene 
• 185967-11-7 (1'S)-3,4-dihydroxy-5-(1,2,2-trimethylcyclopentyl)benzaldehyde 
• 86996-95-4 (S)-5-methyl-3-(1,2,2-trimethylcyclopentyl)benzene-1,2-diol 
• 222022-96-0 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene 

Relevant articles and documents

First synthesis of mastigophorenes A and B, by biomimetic oxidative coupling of herbertenediol

The first synthesis of mastigophorenes A and B by oxidative phenolic coupling of partially protected derivatives of their joint natural monomeric half, herbertenediol, is described. The synthesis starts from this diol itself or from the corresponding aldehyde, both available by isolation from the liverwort, Herbertus aduncus. After transformation of herbertenediol to a chemically appropriate monophenolic coupling precursor, the oxidative dehydrodimerization was brought about using (tert-BuO)2, followed by deprotection to give mastigophorenes A and B in their 'natural' atropisomeric ratio, as isolated from the liverwort.