222027-19-2

Basic information

• Product Name: (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine
• Synonyms: (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine
• CAS NO: 222027-19-2
• Molecular Weight: 291.347
• Mol File: 222027-19-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine(222027-19-2)
• EPA Substance Registry System: (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine(222027-19-2)

Safety Data

• Hazardous Substances Data: 222027-19-2(Hazardous Substances Data)

Upstream product

• 478646-26-3 (2S)-benzyl 1,5-dihydroxypentan-2-ylcarbamate 
• 67436-17-3 dimethyl (S)-N-(benzyloxycarbonyl)glutamate 
• 501-53-1 benzyl chloroformate 
• 119109-58-9 4-(S)-[4-(N-benzyloxycarbonylamino)-5-hydroxy]pentanoic acid methyl ester 
• 4652-65-7 (S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-methyl ester 
• 39538-31-3 methyl (4S)-4-{[(benzyloxy)carbonyl]amino}-5-[(2,5-dioxo-1-pyrrolidinyl)oxy]-5-oxopentanoate 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 222027-12-5 (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(methoxycarbonylethyl)oxazolidine 
• 849437-93-0 (4S)-benzyl 4-(3-hydroxypropyl)-2,2-dimethyloxazolidine-3-carboxylate 

Downstream Products

• 222027-29-4 (S)-2,2-Dimethyl-4-(4-oxo-3-phenoxy-cyclohex-2-enylmethyl)-oxazolidine-3-carboxylic acid benzyl ester 

Relevant articles and documents

BICYCLIC HETEROCYCLES AND THEIR USE AS CCR2 RECEPTOR ANTAGONISTS

The invention is concerned with novel bicyclic compounds of formula (I), wherein A, L, E, F, G, R1, R2, R3, R4, R5, R6, R7, V, W and n are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compound

NOVEL HETEROCYCLYL COMPOUNDS

The invention is concerned with novel heterocyclyl compounds of formula (I) wherein A, X, Y1, Y2, Y3, R3, R4, R5, R6, R7, R8, R9, R10, m, n and p are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medicaments.

Peptidyl α-keto thiazole as potent thrombin inhibitors

We report the synthesis and evaluation of α-keto thiazole derivatives such as D-Phe-Pro-Arg-thiazole 9 as a novel type of thrombin inhibitor. Tripeptidyl α-keto thiazole 9 exhibited the inhibitory activity of thrombin at nanomolar levels and showed a more