478646-26-3

Usage

Uses

Used in Pharmaceutical Industry:
(S)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL is used as a chiral building block for the synthesis of enantiopure compounds, which are essential in the development of chiral drugs. (S)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL's unique structure allows for the creation of pharmaceuticals with specific biological activities, improving the efficacy and safety of medications.
Used in Fine Chemicals Industry:
In the fine chemicals industry, (S)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL serves as an important intermediate for the production of various bioactive molecules. Its versatility in chemical reactions enables the synthesis of a wide range of specialty chemicals with specific applications in fields such as agriculture, fragrances, and dyes.
Used in Organic Synthesis:
(S)-2-N-CBZ-AMINO-PENTANE-1,5-DIOL is utilized as a key intermediate in organic synthesis, where its functional groups facilitate various chemical reactions. This allows for the creation of complex molecular structures with specific properties, contributing to the advancement of chemical research and the development of novel compounds with potential applications in various industries.

InChI:InChI=1/C13H19NO4/c15-8-4-7-12(9-16)14-13(17)18-10-11-5-2-1-3-6-11/h1-3,5-6,12,15-16H,4,7-10H2,(H,14,17)/t12-/m0/s1

Upstream product

• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 67436-17-3 dimethyl (S)-N-(benzyloxycarbonyl)glutamate 

Downstream Products

• 849437-93-0 (4S)-benzyl 4-(3-hydroxypropyl)-2,2-dimethyloxazolidine-3-carboxylate 
• 21946-71-4 (2S)-aminopentan-1,5-diol 
• 188947-24-2 (S)-4-((E)-4-Cyano-but-3-enyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 222027-19-2 (4S)-3-(benzyloxycarbonyl)-2,2-dimethyl-4-(3-oxo-propyl)oxazolidine 
• 849438-21-7 (2S,9S)-methyl 9-9H-fluoren-9-ylmethoxycarbonylamino-2-tert-butoxycarbonylamino-10-tert-butyldiphenylsilyloxydecanoate 
• 849438-20-6 (4S)-tert-butyl 4-(7S)-7-9H-fluoren-9-ylmethoxycarbonylmino-8-tert-butyldiphenylsilyloxyoctyl-2,2-dimethyloxazolidine-3-carboxylate 
• 849438-18-2 (4S)-tert-butyl 4-(7S)-7-benzyloxycarbonylamino-8-tert-butyldiphenylsilyloxyoct-3-enyl-2,2-dimethyloxazolidine-3-carboxylate 
• 856660-68-9 (4S)-tert-butyl 4-(7S)-7-benzyloxycarbonylamino-8-tert-butyldiphenylsilyloxy-3-hydroxy-4-phenylsulfonyloctyl-2,2-dimethyloxazolidine-3-carboxylate 
• 856660-63-4 (2S)-benzyl 1-tert-butyldiphenylsilyloxy-5-phenylsulfonylpentan-2-ylcarbamate 
• 849437-97-4 (4S)-benzyl 2,2-dimethyl-4-(3-phenylsulfonylpropyl)oxazolidine-3-carboxylate 
• 849438-04-6 (2S)-benzyl 1-hydroxy-5-phenylsulfonylpentan-2-ylcarbamate 
• 856660-84-9 (S)-4-(3-Methanesulfonyloxy-propyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid benzyl ester 
• 856660-75-8 4-[4-benzenesulfonyl-7-benzyloxycarbonylamino-8-(tert-butyl-diphenyl-silanyloxy)-4-methyl-3-oxo-octyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 856660-74-7 4-[4-benzenesulfonyl-7-benzyloxycarbonylamino-8-(tert-butyl-diphenyl-silanyloxy)-3-oxo-octyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

A new diastereoselective synthetic approach to the enantiopure peptidomimetic scaffold 2-oxo-1-azabicyclo[4.4.0]decane

A general method for the synthesis of unsubstituted and C-7-substituted azabicyclo[4.4.0]decane dipeptides (23, 30a, and 30b) that can serve as dipeptide mimetics has been developed. The key step of this new method involves the coupling reaction of the ox

Synthesis of orthogonally protected enantiopure 2,9-diaminodecanedioic acid: A model for a new general method for the synthesis of orthogonally protected α,α′-diaminodicarboxylic acids

A new method for the synthesis of orthogonally protected enantiopure α,α′-diaminodicarboxylic acids is described. A key step involves the Julia olefination of an aldehyde and a sulfone, both of which are derived from an optically pure dicarboxylic amino a

Peptidyl α-keto thiazole as potent thrombin inhibitors

We report the synthesis and evaluation of α-keto thiazole derivatives such as D-Phe-Pro-Arg-thiazole 9 as a novel type of thrombin inhibitor. Tripeptidyl α-keto thiazole 9 exhibited the inhibitory activity of thrombin at nanomolar levels and showed a more