4652-65-7

Basic information

• Product Name: Z-GLU(OME)-OH
• Synonyms: N-ALPHA-CARBOBENZOXY-L-GLUTAMIC ACID GAMMA-METHYL ESTER;Z-GLU(OME)-OH;Z-GLUTAMIC ACID(OME)-OH;Z-L-GLUTAMIC ACID GAMMA-METHYL ESTER;CBZ-GLU(OME)-OH;BENZYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-METHYL ESTER;Cbz-L-glutamicacid4-methylester;N-Benzyloxycarbonyl-L-glutamic acid GAMMA-methyl ester
• CAS NO: 4652-65-7
• Molecular Formula: C₁₄H₁₇NO₆
• Molecular Weight: 295.29
• Mol File: 4652-65-7.mol
• Article Data: 16

Chemical Properties

• Melting Point: 76℃
• Boiling Point: 510.6 °C at 760 mmHg
• Flash Point: 262.6 °C
• Appearance: /
• Density: 1.272 g/cm³
• Vapor Pressure: 3.01E-11mmHg at 25°C
• Refractive Index: 1.535
• Storage Temp.: -15°C
• Solubility: soluble in Methanol
• CAS DataBase Reference: Z-GLU(OME)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-GLU(OME)-OH(4652-65-7)
• EPA Substance Registry System: Z-GLU(OME)-OH(4652-65-7)

Safety Data

• Hazardous Substances Data: 4652-65-7(Hazardous Substances Data)

Usage

Chemical Properties

White powder

Uses

Z-Glu(OMe)-OH is an inhibitor of fibrin stabilizing factor.

InChI:InChI=1/C14H17NO6/c1-20-12(16)8-7-11(13(17)18)15-14(19)21-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,15,19)(H,17,18)/t11-/m0/s1

Upstream product

• 124-41-4 sodium methylate 
• 4124-76-9 N-(benzyloxycarbonyl)-L-glutamic acid anhydride 
• 67-56-1 methanol 
• 57933-83-2 Isopropenyl chloroformate 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 67436-17-3 dimethyl (S)-N-(benzyloxycarbonyl)glutamate 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 1499-55-4 L-glutamic acid 5-methyl ester 
• 1499-55-4 2-Amino-pentanedioic acid 5-methyl ester 
• 501-53-1 benzyl chloroformate 
• 3077-51-8 γ-methyl L-glutamate hydrochloride 
• 56-86-0 L-glutamic acid 
• 79-22-1 methyl chloroformate 
• 4124-76-9 Cbz-L-glutamic anhydride 

Downstream Products

• 2503-33-5 L-N-benzyloxycarbonylglutamate de 5-methylglycinate d'ethyle 
• 57732-63-5 1-tert-butyl 5-methyl (2S)-2-{[(benzyloxy)carbonyl]amino}pentanedioate 
• 5891-45-2 (S)-2-(benzyloxycarbonylamino)pentanedioic acid tert-butyl ester 
• 95022-60-9 benzyloxycarbonyl-L-glutamic acid α-tert-butyl ester γ-hydrazide 
• 910908-63-3 N-Carbobenzoxy-<α-p-nitro-benzyl,γ-methyl>-L-glutamat 
• 36933-22-9 L-N-Z-γ-methyl-N-<2-(5-methoxy-3-indolyl)ethyl>isoglutamide 
• 27169-29-5 Bz-Glu-γ-OMe-Glu-γ-OMe-OMe 
• 5507-21-1 N-Benzyloxycarbonyl-γ-O-methyl-L-glutamyl-<γ-O-ethyl-L-glutaminsaeure-(4-nitro-benzylester)> 
• 205252-10-4 (S)-4-Benzyloxycarbonylamino-4-(6-hydroxy-hexylcarbamoyl)-butyric acid methyl ester 
• 39538-31-3 methyl (4S)-4-{[(benzyloxy)carbonyl]amino}-5-[(2,5-dioxo-1-pyrrolidinyl)oxy]-5-oxopentanoate 
• 988-75-0 N-benzyloxycarbonyl-L-glutamyl-L-tyrosine 
• 51298-63-6 C₁₄H₁₆ClNO₅ 
• 864282-48-4 Cbz-Glu(OMe)PhePhe-NH-C₁₀H₂₀O₃-NH-Boc 
• 1306771-19-6 C₁₈H₂₈N₈O₆ 

Relevant articles and documents

Total Synthesis of Indolizidine Alkaloids via Nickel-Catalyzed (4 + 2) Cyclization

A Ni-catalyzed (4 + 2) cycloaddition of alkynes and azetidinones toward piperidinones was used as key reaction in the enantioselective synthesis of naturally occurring indolizidine alkaloids. The reaction benefits from the use of an easily accessible azet

METHOD FOR PREPARING 3-[(3S)-7-BROMO-2-OXO-5-(PYRIDIN-2-YL)-2,3-DIHYDRO-1H-[1,4]-BENZODIAZEPIN-3-YL] PROPIONIC ACID METHYL ESTER, AND COMPOUNDS USEFUL IN THAT METHOD

The present invention relates to a method for preparing 3-[(3S)-7- bromo-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-IH-[l,4]-benzodiazepin-3-yl] propionic acid methyl ester from (2-amino-5-bromo-phenyl)-pyridin-2- yl-methanone. The present invention also relates

Constrained Cyclic β,γ-Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution

We describe here an efficient synthesis of both diastereomers of cyclic β,γ-diamino acids starting from l-glutamic acid, based on the Blaise reaction. We show that by changing the protecting group, we can access either the five-membered-ring lactam, which