222175-00-0Relevant academic research and scientific papers
Metal-Organic Self-Assembled Trefoil Knots for C - Br Bond Activation
Prakasam, Thirumurugan,Devaraj, Anthonisamy,Saha, Rupak,Lusi, Matteo,Brandel, Jeremy,Esteban-Gómez, David,Platas-Iglesias, Carlos,Olson, Mark Anthony,Mukherjee, Partha Sarathi,Trabolsi, Ali
, p. 1907 - 1914 (2019)
Synthesizing molecular knots that mimic the catalytic functionality of stereospecific or stereoselective enzymes are an intriguing task in chemistry. Synthetic anion receptors even with moderate halide binding affinities may catalyze chemical reactions in
A facile tandem construction of C-O and C-C bonds: A novel one-pot transformation of Baylis-Hillman adducts into 2-benzoxepines
Basavaiah, Deevi,Sharada, Duddu S.,Veerendhar, Ainelly
, p. 3081 - 3083 (2004)
A facile and one-pot synthesis of 2-benzoxepines, from Baylis-Hillman adducts that is, alkyl 3-aryl-3-hydroxy-2-methylenepropanoates, via treatment with HCHO in the presence of concd H2SO4, involving tandem construction of C-O and C-C bonds via Prins-type and Friedel-Crafts reactions, is described.
Palladium-Catalyzed Allyl-Allyl Reductive Coupling of Allylamines or Allylic Alcohols with H2as Sole Reductant
Zhou, Xibing,Zhang, Guoying,Huang, Renbin,Huang, Hanmin
supporting information, p. 365 - 369 (2021/01/26)
Catalytic carbon-carbon bond formation building on reductive coupling is a powerful method for the preparation of organic compounds. The identification of environmentally benign reductants is key for establishing an efficient reductive coupling reaction. Herein an efficient strategy enabling H2 as the sole reductant for the palladium-catalyzed allyl-allyl reductive coupling reaction is described. A wide range of allylamines and allylic alcohols as well as allylic ethers proceed smoothly to deliver the C-C coupling products under 1 atm of H2. Kinetic studies suggested that the dinuclear palladium species was involved in the catalytic cycle.
Combining NHC-Cu and Bronsted base catalysis: Enantioselective allylic substitution/conjugate additions with alkynylaluminum reagents and stereospecific isomerization of the products to trisubstituted allenes
Dabrowski, Jennifer A.,Haeffner, Fredrik,Hoveyda, Amir H.
supporting information, p. 7694 - 7699 (2013/08/23)
All-catalytic route to trisubstituted allenes: The first examples of catalytic enantioselective allylic substitution reactions that involve alkyne-based nucleophiles and lead to products having tertiary stereogenic centers are followed by an exceptionally
Ni(0)-promoted hydroxycarboxylation of 1,2-dienes by reaction with CO 2 and O2
Aoki, Masao,Izumi, Sawa,Kaneko, Motomu,Ukai, Kazutoshi,Takaya, Jun,Iwasawa, Nobuharu
, p. 1251 - 1253 (2007/10/03)
Figure presented A novel method for the preparation of hydroxy carboxylic acid derivatives has been developed by O2-oxidation of π-allylnickel intermediates generated by Ni(0)-mediated coupling of 1,2-dienes with CO2.
Stereoselective synthesis of a potent human NK1 receptor antagonist via acyl-Claisen rearrangement
Raubo, Piotr,Giuliano, Claudio,Hill, Alastair W.,Huscroft, Ian T.,London, Clare,Reeve, Austin,Seward, Eileen M.,Swain, Christopher G.,Kulagowski, Janusz J.
, p. 600 - 604 (2007/10/03)
Stereoselective synthesis of the tetrahydropyran derivative 1 is reported. Diastereoselective acyl-Claisen rearrangement was employed for formation of C3 and C4 chiral centres on the tetrahydropyran ring. Georg Thieme Verlag Stuttgart.
The Baylis-Hillman reaction: One-pot stereoselective synthesis of methyl (2E)-3-aryl-2-hydroxymethylprop-2-enoates
Basavaiah,Padmaja,Satyanarayana
, p. 1662 - 1664 (2007/10/03)
A facile, simple and one-pot conversion of methyl 3-aryl-3-hydroxy-2-methylenepropanoates into methyl (2E)-3-aryl-2-hydroxymethylprop-2-enoates via the sequential treatment with acetic anhydride/trimethylsilyl trifluoromethanesulfonate (TMSOTf) and potassium carbonate/methanol is described.
