22219-35-8Relevant academic research and scientific papers
Supported transition-metal catalysts for the C-C coupling reaction between ethene and diazoalkanes
Schneider,Moehring,Werner
, p. 181 - 186 (1996)
The preparation of a series of immobilized transition-metal catalysts are reported. The catalysts were obtained by chemisorption of either rhodium(I) or iridium(I) complexes [MX(C2H4)2]n (M = Rh, Ir; X = Cl, OAc
The Cyclopropane Ring as a Reporter of Radical Leaving-Group Reactivity for Ni-Catalyzed C(sp3)-O Arylation
Mills, L. Reginald,Monteith, John J.,Dos Passos Gomes, Gabriel,Aspuru-Guzik, Alán,Rousseaux, Sophie A. L.
, p. 13246 - 13254 (2020/09/01)
The ability to understand and predict reactivity is essential for the development of new reactions. In the context of Ni-catalyzed C(sp3)-O functionalization, we have developed a unique strategy employing activated cyclopropanols to aid the design and optimization of a redox-active leaving group for C(sp3)-O arylation. In this chemistry, the cyclopropane ring acts as a reporter of leaving-group reactivity, since the ring-opened product is obtained under polar (2e) conditions, and the ring-closed product is obtained under radical (1e) conditions. Mechanistic studies demonstrate that the optimal leaving group is redox-active and are consistent with a Ni(I)/Ni(III) catalytic cycle. The optimized reaction conditions are also used to synthesize a number of arylcyclopropanes, which are valuable pharmaceutical motifs.
Arylcyclopropane Photochemistry. Effects of Electron-Donating and Electron-Withdrawing Aromatic Substituents on the Photochemical Rearrangements of 1,1-Diarylcyclopropanes.
Hixson, Stephen S.,Franke, Lothar A.
, p. 2706 - 2711 (2007/10/02)
Irradiation of 1,1-diarylcyclopropanes 4a-g, having substituents X and Y at the para positions of the aromatic rings, afforded 1,1-diarylpropenes 5a-g and 1-arylindans 6a-f.The rate constants of these (singlet state) reactions, determined from the reactan
