22220-39-9Relevant academic research and scientific papers
Preparation method of phenyl tetrahydroisoquinoline
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, (2020/09/09)
The invention provides a preparation method of phenyl tetrahydroisoquinoline, belonging to the field of pharmaceutical chemicals. According to the method, dihydro-1H-2-benzopyran-1-one is used as a starting material and is subjected to Grignard reagent ring opening, chlorination, substitution reaction and hydrazinolysis to obtain a phenyl tetrahydroisoquinoline compound. The compound produced by the method has the characteristics of high purity, high yield, low cost, simple operation and stable process.
