222317-29-5Relevant articles and documents
A nucleophilic 1,3-rearrangement leading to 3,4-disubstituted 3,4-dihydroquinolines
He, Chun-Xian,Jiang, Zhi-Bo,Cui, Hua-Qing,Yin, Da-Li
, p. 1036 - 1039 (2016)
A new nucleophilic 1,3-rearrangement is observed when treating 2-methoxyquinolino-3-lithium with an α-C substituted deoxybenzoin, and this rearrangement yielded an unusual 3,4-disubstituted 3,4-dihydroquinoline. Several similar reactions were designed and executed to investigate this novel 1,3-rearrangement, and a mechanism involving a nucleophilic addition and a following 1,3-rearrangement with an unusual dearomatization on the quinoline ring is proposed.