222320-29-8Relevant academic research and scientific papers
Synthesis of some impurities and/or degradation products of atorvastatin
Stach, Jan,Havlicek, Jaroslav,Placek, Lukas,Radl, Stanislav
, p. 229 - 246 (2008)
Synthesis of some impurities and/or degradation products of atorvastatin, calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl) pyrrol-1-yl]-3,5-dihydroxyheptanoate, is described. These include its desfluoro analog, the corresponding (3S,5S)-and (3S,5R)-epimers, atorvastatin lactone, and some other potential impurities. The synthesized compounds as well as the corresponding intermediates were characterized by 1H NMR, 13C NMR and MS.
An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives
Sagyam, Rajeshwar Reddy,Vurimidi, Himabindu,Padi, Pratap Reddy,Ghanta, Mahesh Reddy
, p. 923 - 926 (2008/03/29)
(Chemical Equation Presented) An efficient synthesis of highly substituted pyrrole and bis pyrrole derivatives is reported.
