444577-70-2 Usage
Uses
Used in Pharmaceutical Industry:
N,3-Diphenyl-2-(2-methyl-1-oxopropyl)4-oxo-N-benzenebutanamide (Mixture of Diastereomers) is used as a byproduct in the production of Atorvastatin intermediates. It plays a crucial role in the synthesis of Atorvastatin impurities, which are essential for the development and manufacturing of the final pharmaceutical product.
Used in Chemical Research:
As a complex organic compound, N,3-Diphenyl-2-(2-methyl-1-oxopropyl)4-oxo-N-benzenebutanamide (Mixture of Diastereomers) can be utilized in various chemical research applications. It can serve as a starting material for the synthesis of other related compounds or be used to study the properties and behavior of diastereomers in different chemical reactions and processes.
Check Digit Verification of cas no
The CAS Registry Mumber 444577-70-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,4,4,5,7 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 444577-70:
(8*4)+(7*4)+(6*4)+(5*5)+(4*7)+(3*7)+(2*7)+(1*0)=172
172 % 10 = 2
So 444577-70-2 is a valid CAS Registry Number.
InChI:InChI=1/C26H25NO3/c1-18(2)24(28)23(26(30)27-21-16-10-5-11-17-21)22(19-12-6-3-7-13-19)25(29)20-14-8-4-9-15-20/h3-18,22-23H,1-2H3,(H,27,30)
444577-70-2Relevant academic research and scientific papers
Synthesis of some impurities and/or degradation products of atorvastatin
Stach, Jan,Havlicek, Jaroslav,Placek, Lukas,Radl, Stanislav
, p. 229 - 246 (2008/12/22)
Synthesis of some impurities and/or degradation products of atorvastatin, calcium (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl) pyrrol-1-yl]-3,5-dihydroxyheptanoate, is described. These include its desfluoro analog, the corresponding (3S,5S)-and (3S,5R)-epimers, atorvastatin lactone, and some other potential impurities. The synthesized compounds as well as the corresponding intermediates were characterized by 1H NMR, 13C NMR and MS.
