22248-27-7

Basic information

• Product Name: 2(5H)-Furanone, 3-(4-methoxyphenyl)-
• CAS NO: 22248-27-7
• Molecular Formula: C11H10O3
• Molecular Weight: 190.199
• Mol File: 22248-27-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 3-(4-methoxyphenyl)-(22248-27-7)
• EPA Substance Registry System: 2(5H)-Furanone, 3-(4-methoxyphenyl)-(22248-27-7)

Safety Data

• Hazardous Substances Data: 22248-27-7(Hazardous Substances Data)

Upstream product

• 31555-04-1 ethyl 4-hydroxy-2-butynoate 
• 5720-07-0 4-methoxyphenylboronic acid 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 50415-68-4 methyl 2-(4-methoxyphenyl)prop-2-enoate 
• 50-00-0 formaldehyd 
• 51747-42-3 2-(4-methoxy-phenyl)-acrylic acid 
• 696-62-8 para-iodoanisole 
• 201230-82-2 carbon monoxide 
• 768-60-5 4-methoxyphenylacetylen 

Relevant articles and documents

Reductive Carbonylation of Acetylenes under Water-Gas Shift Reaction Conditions. Synthesis of Furan-2(5H)-ones from Terminal and Non-substituted Acetylenes

Under water-gas reaction conditions terminal and non-substituted acetylenes are selectively converted into furan-2(5H)-ones by catalysis with a rhodium carbonyl cluster.

Cobalt-Catalyzed Vinylic C-H Addition to Formaldehyde: Synthesis of Butenolides from Acrylic Acids and HCHO

A carboxyl-assisted C-H functionalization of acrylic acids with formaldehyde to give butenolides is described. It is the first time that the addition of an inert vinylic C-H bond to formaldehyde has been achieved via cobalt-catalyzed C-H activation. The unique reactivity of the cobalt species was observed when compared with related Rh or Ir catalysts. γ-Hydroxymethylated butenolides were produced by the treatment of Na2CO3 after the catalytic reaction in one pot.

Regioselective Pd-catalyzed alkylative lactonizations of 4-hydroxy-2-alkynecarboxylates with organoboronic acids

The Pd-catalyzed addition of organoboronic acids to 4-hydroxy-2- alkynecarboxylates and in situ lactonization gave the butenolides with a high control of regioselectivity.