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222530-34-9

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222530-34-9 Usage

Uses

(1S,3R)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid is used in preparation of indazolyl-pyrimidines and related heterocycles as CDK inhibitors and their use as pharmaceuticals.

Check Digit Verification of cas no

The CAS Registry Mumber 222530-34-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,2,2,5,3 and 0 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 222530-34:
(8*2)+(7*2)+(6*2)+(5*5)+(4*3)+(3*0)+(2*3)+(1*4)=89
89 % 10 = 9
So 222530-34-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H21NO4/c1-12(2,3)17-11(16)13-9-6-4-5-8(7-9)10(14)15/h8-9H,4-7H2,1-3H3,(H,13,16)(H,14,15)/t8-,9+/m1/s1

222530-34-9 Well-known Company Product Price

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  • TCI America

  • (B3539)  (1S,3R)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid  >97.0%(GC)(T)

  • 222530-34-9

  • 1g

  • 6,990.00CNY

  • Detail

222530-34-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name (1S,3R)-3-(tert-Butoxycarbonylamino)cyclohexanecarboxylic Acid

1.2 Other means of identification

Product number -
Other names (1S,3R)-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:222530-34-9 SDS

222530-34-9Relevant articles and documents

Polycyclic amide derivative as CDK9 inhibitor, and preparation method and application thereof

-

, (2021/07/24)

The invention belongs to the technical field of polycyclic amide derivatives, and particularly relates to a polycyclic amide derivative as a CDK9 inhibitor, and a preparation method and application thereof. The polycyclic amide derivative shows excellent CDK9 enzyme inhibitory activity, and can be used for preparing drugs for treating cancers, especially hematologic cancers including acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia, follicular lymphoma and the like and solid tumors, such as acute myeloid leukemia, multiple myeloma, chronic lymphocytic leukemia and follicular lymphoma, including breast cancer, prostate cancer, ovarian cancer, hepatocellular carcinoma, pancreatic cancer, kidney cancer, stomach cancer, colorectal cancer, lung cancer and the like.

PYRAZOLYL COMPOUNDS AND METHODS OF USE THEREOF

-

Paragraph 0374-0379; 0192-0193; 0532-0535, (2020/05/14)

Compounds having activity as chemotherapeutic agents are provided. The compounds have the following structure (I): or a pharmaceutically acceptable salt, stereoisomer, isotopic form or prodrug thereof, wherein R1a, R1b, R1c, R1d, L, and are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods for treating cancer (e.g., hematological cancers) are also provided.

Synthesis of cyclic γ-amino acids for foldamers and peptide nanotubes

Rodriguez-Vazquez, Nuria,Salzinger, Stephan,Silva, Luis F.,Amorin, Manuel,Granja, Juan R.

, p. 3477 - 3493 (2013/07/11)

Cyclic γ-amino acids are molecular building blocks of great interest in peptide and foldamer chemistry, as they allow the preparation of new structures that are not found in Nature. In this paper, we describe the synthesis of cyclic γ-amino acids that have a cis relationship between the amino and the carboxylic acid groups. This arrangement, in most cases, induces the resulting peptides to adopt a flat conformation, which makes them appropriate for the design of foldamers that adopt β-sheet-type structures. We describe the synthesis of cyclic γ-amino acids that have a cis relationship between the amino and the carboxylic acid groups. This makes them suitable for the design of foldamers that adopt β-sheet-type structures.

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