16636-51-4

Basic information

• Product Name: CIS-3-AMINOCYCLOHEXANECARBOXYLICACID
• Synonyms: CIS-3-AMINOCYCLOHEXANECARBOXYLICACID;cis-3-Aminocyclohexane-1-carboxylicacid;(1R,3S)-rel-3-Aminocyclohexanecarboxylic acid;cis-3-Aminocyclohexanecarboxylic Acid;(1R,3S)-3-aminocyclohexane-1-carboxylic acid;Cyclohexanecarboxylic acid, 3-amino-, (1R,3S)-rel-;rel-(1R,3S)-3-aminocyclohexane-1-carboxylic acid
• CAS NO: 16636-51-4
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.18362
• Mol File: 16636-51-4.mol
• Article Data: 11

Chemical Properties

• Melting Point: 278 °C
• Boiling Point: 280°C at 760 mmHg
• Flash Point: 123.1°C
• Appearance: /
• Density: 1.133g/cm³
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.503
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 3.99±0.10(Predicted)
• Water Solubility: Soluble in water
• CAS DataBase Reference: CIS-3-AMINOCYCLOHEXANECARBOXYLICACID(CAS DataBase Reference)
• NIST Chemistry Reference: CIS-3-AMINOCYCLOHEXANECARBOXYLICACID(16636-51-4)
• EPA Substance Registry System: CIS-3-AMINOCYCLOHEXANECARBOXYLICACID(16636-51-4)

Safety Data

• Hazardous Substances Data: 16636-51-4(Hazardous Substances Data)

Usage

General Description

Cis-3-Aminocyclohexanecarboxylic Acid is a cyclic, non-proteinogenic amino acid with potential antineoplastic activities. This organic compound falls under the category of aminocyclohexanecarboxylic acids and derivatives. Its systematic name is (1R,3S)-3-aminocyclohexanecarboxylic acid which indicates its specific stereochemistry. The health benefits and potential risks of this chemical have not been thoroughly outlined yet, as it is mostly used in laboratory research settings, given its potential anticancer properties. Overall, this synthetic amino acid is an important compound for biochemical research.

InChI:InChI=1/C7H13NO2/c8-6-3-1-2-5(4-6)7(9)10/h5-6H,1-4,8H2,(H,9,10)

Upstream product

• 99-05-8 meta-aminobenzoic acid 
• 123-51-3 i-Amyl alcohol 
• 334932-13-7 3-[(tert-butoxycarbonyl)amino]cyclo-hexanecarboxylic acid 
• 4720-83-6 6-oxabicyclo[3.2.1]oct-3-en-7-one 
• 116724-13-1 trans rac-cyclohexyl 1,3-dicarboxylic acid 

Downstream Products

• 53084-60-9 ethyl 3-aminocyclohexanecarboxylate 
• 218772-92-0 (±)-cis-3-((tert-butoxycarbonyl)amino)cyclohexanecarboxylic acid 
• 334932-13-7 3-[(tert-butoxycarbonyl)amino]cyclo-hexanecarboxylic acid 
• 712313-64-9 methyl 3-aminocyclohexanecarboxylate hydrochloride 
• 925921-14-8 3-hydroxymethyl-1-cyclohexylamine 
• 87091-29-0 methyl 3-aminocyclohexanecarboxylate 
• 1001010-72-5 3-(4-oxo-2-thioxo-thiazolidin-3-yl)-cyclohexanecarboxylic acid 
• 218772-92-0 racemic trans-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylic acid 
• 1352568-46-7 (S)-2-((1S,3R)-3-aminocyclohexanecarboxamido)-3-phenylpropanoic acid hydrochloride 
• 1352568-37-6 C₂₁H₂₅N₃O₃ 
• 1035325-38-2 (1R,3S)-3-(1H-benzo[d]imidazol-2-yl)cyclohexanamine 
• 1352568-45-6 (S)-benzyl 2-((1S,3R)-3-(((benzyloxy)carbonyl)amino)cyclohexanecarboxamido)-3-phenylpropanoate 
• 952616-39-6 (1S,3R)-3-(((benzyloxy)carbonyl)amino)cyclohexanecarboxylic acid 
• 1580507-71-6 3-(dimethylamino)cyclohexanecarboxylic acid hydrochloride 

Relevant articles and documents

New cyclic peptide assemblies with hydrophobic cavities: The structural and thermodynamic basis of a new class of peptide nanotubes

A new class of self-assembling peptides based on cyclic peptides made of alternating 3-aminocyclohexanecarboxylic acid (γ-Acc) and α-amino acids is described. The studied cylindrical assemblies are models for a new class of self-assembling peptide nanotub

Self-assembled peptide tubelets with 7 A pores

Here we report the preparation and structural characteristics of self-assembling peptide tubelets composed of 32-membered rings formed of alternating cx-amino acids and cis-3-aminocyclohexanecarboxylic acids. The tubelets possess a partial hydrophobic cor

2-aminopyridine derivatives and combinatorial libraries thereof

The present invention relates to novel 2-aminopyridine derivative compounds of the following formula: wherein R1to R5have the meanings provided herein. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing 2-aminopyridine derivative compounds.