41235-88-5

Basic information

• Product Name: (1R,3S)-3-aminocyclohexanecarboxylic acid
• Synonyms: (1R,3S)-3-Ammoniocyclohexanecarboxylate; cyclohexanecarboxylic acid, 3-amino-, (1R,3S)-
• CAS NO: 41235-88-5
• Molecular Formula: C₇H₁₃NO₂
• Molecular Weight: 143.1836
• Mol File: 41235-88-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 280°C at 760 mmHg
• Flash Point: 123.1°C
• Density: 1.133g/cm³
• Vapor Pressure: 0.00103mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: (1R,3S)-3-aminocyclohexanecarboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S)-3-aminocyclohexanecarboxylic acid(41235-88-5)
• EPA Substance Registry System: (1R,3S)-3-aminocyclohexanecarboxylic acid(41235-88-5)

Safety Data

• Hazardous Substances Data: 41235-88-5(Hazardous Substances Data)

Upstream product

• 99-05-8 meta-aminobenzoic acid 
• 123-51-3 i-Amyl alcohol 
• 81131-37-5 (1R,3S)-3-phthalimidocyclohexanecarboxylic acid 
• 16205-98-4 3-oxo-cyclohexanecarboxylic acid 
• 15111-56-5 ethyl-3-cyclohexene-1-carboxylate 
• 81086-72-8 5-Bromo-cyclohex-3-enecarboxylic acid ethyl ester 
• 586-38-9 3-Methoxybenzoic acid 
• 81131-38-6 (1S,3R)-3-phthalimidocyclohexanecarboxylic acid 
• 4720-83-6 6-oxabicyclo[3.2.1]oct-3-en-7-one 
• 116724-13-1 trans rac-cyclohexyl 1,3-dicarboxylic acid 
• 81201-62-9 (d,l)-cis-3-phthalimidocyclohex-4-ene-1-carboxylic acid 
• 81202-30-4 (1S,5S)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclohex-3-enecarboxylic acid 
• 81086-73-9 ethyl cis-5-phthalimidocyclohex-3-ene-1-carboxylate 
• 81202-29-1 (1R,5R)-5-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-cyclohex-3-enecarboxylic acid 

Relevant articles and documents

Development of an Enantioselective Novozym 435 Mediated Acetylation for the Preparation of (1S,3R)-3-Acetamidocyclohexane-1-carboxylic Acid

Starting from a cheap and readily available starting material, a short and enantioselective route to (1S,3R)-3-acetamidocyclohexane-1-carboxylic acid was developed. The key steps were a rhodium catalyzed hydrogenation of 3-aminobenzoic acid and an enantioselective Novozym 435 mediated acetylation of racemic isopropyl 3-aminocyclohexanecarboxylate.

Inhibitors of protein kinases

Compounds of general Formula (I): wherein R1, R2, R3, Ra, A, B and x are as defined herein are inhibitors of protein kinases in particular members of the cyclin-dependent kinase family and/or the glycogen synthase kinase 3 family and are useful in preventing and/or treating any type of pain, inflammatory disorders, cancer, immunological diseases, proliferative diseases, infectious diseases, cardiovascular diseases, metabolic disorders, renal diseases, neurologic and neuropsychiatric diseases and neurodegenerative diseases.

Self-assembled peptide tubelets with 7 A pores

Here we report the preparation and structural characteristics of self-assembling peptide tubelets composed of 32-membered rings formed of alternating cx-amino acids and cis-3-aminocyclohexanecarboxylic acids. The tubelets possess a partial hydrophobic cor