222548-10-9

Usage

Uses

Used in Agricultural Chemicals Industry:
2-Pyridinol, 3,5-dinitrois used as an intermediate in the manufacturing of pesticides and herbicides. Its chemical properties make it suitable for the development of effective agricultural chemicals that protect crops from pests and weeds.
Used in Pharmaceutical Industry:
2-Pyridinol, 3,5-dinitrocan also be used as a building block in the synthesis of pharmaceuticals. Its unique structure allows for the creation of new compounds with potential therapeutic applications.
Used in Industrial Chemicals Synthesis:
In addition to its applications in agriculture and pharmaceuticals, 2-Pyridinol, 3,5-dinitrois utilized in the synthesis of various industrial chemicals. Its versatility and unique properties make it a valuable component in the development of new chemical products.

Upstream product

• 142-08-5 2-Pyridone 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 5418-51-9 5-nitro-2-pyridone 
• 2578-45-2 2-chloro-3,5-dinitropyridine 
• 25864-34-0 2-amino-3,5-dinitro-6-methylpyridine 
• 13472-80-5 2-hydroxy-3,5-diiodopyridine 
• 142-08-5 2-hydroxypyridin 
• 1824-81-3 2-Amino-6-methylpyridine 
• 6635-31-0 6-hydroxy-5-nitronicotinic acid 
• 7697-37-2 nitric acid 

Relevant academic research and scientific papers

Amino- and hydroxymethylation of hydride adducts of 2-hydroxy-3,5- dinitropyridine

A series of 1,5-dinitro-3,3-diazabicyclo[3.3.1]nonan-2-one derivatives has been synthesized by Mannich condensation of the hydride adduct of 2-hydroxy-3,5-dinitropyridine with formaldehyde and primary amines. The structure of the obtained compounds was proved by NMR spectroscopy.

Fluorescence Properties and Exciplex Formation of Emissive Naphthyridine Derivatives: Application as Sensors for Amines

Water-soluble donor–acceptor-type fluorophore 15Nap-Cl having two trifluoromethyl groups and a Cl group on a 1,5-aminonaphthyridine framework was prepared. Fluorophore 15Nap-Cl showed strong solvatochromic fluorescence, and, as the solvent polarity increased, a bathochromic shift was observed accompanied by an increase in the fluorescence quantum yield. In addition, in the presence of amines such as ethylamine, diethylamine, and aniline, further considerable bathochromic shifts in the fluorescence were observed. Density functional calculations identified the source of the fluorescence behavior as exciplex formation between 15-Nap-Cl and the corresponding amine. The fluorescence behavior was exploited to fabricate a sensor that can identify various primary, secondary, and tertiary amines.

Reactivity of heterocyclic compounds in nitration. 8. Nitration of 3-hydroxypyridine and its substituted forms

Nitration of 3-hydroxypyridine and its substituted forms has been studied under various conditions. It is shown that, depending on the reaction temperature and the nitrating agent, the end products of the synthesis can be 3-hydroxy-2,6-dinitropyridine or 3-hydroxy-2,4,6-trinitropyridine. The possibility of substitutional nitration of iodine derivatives of 2- and 3-hydroxypyridine is demonstrated. 1999 Kluwer Academic/Plenum Publishers.

Synthesis and Reactions of Dinitrated Amino and Diaminopyridines

Nitration of amino- and diaminopyridines and -picolines led, in unexpected one-step reactions, to dinitrated derivatives.Dinitropicolines gave styrylpiridines, and 2-amino-6-hydroxy-3,5-dinitropyridine was transformed by the thermolysis of its azido deriv

THE REACTIVITY OF SOME PRIMARY AMINES IN SN2Ar REACTIONS WITH 2-CHLORO-3,5-DINITROPYRIDINE

Rate constants for SN2Ar reactions of 2-chloro-3,5-dinitropyridine (1) with butylamine, glycine, glycylglycine and ethylenediamine monohydrochloride, in water at 1.0 mol dm-3 constant ionic strength and 25 deg C, have been determined.The Broensted β coefficient is 0.51.The reactivities of 1 and 2-chloro-1-methylpyridinium ion (2) with these primary amines were compared using a derived Edwards equation.One could infer that 2 tends to undergo more charge interaction than 1 because of the quaternary nitrogen of the pyridinium ring of 2.A coordination of the substrates, 1, 2 and 4-chloro-1-methylpyridinium ion (3) dependent on the degree of hardness and softness is presented.