222548-10-9

Basic information

• Product Name: 2-Pyridinol, 3,5-dinitro-
• Synonyms: 2-Pyridinol, 3,5-dinitro-
• CAS NO: 222548-10-9
• Molecular Formula: C5H3 N3 O5
• Molecular Weight: 185.09
• Product Categories: Pyridines
• Mol File: 222548-10-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 321°Cat760mmHg
• Flash Point: 147.9°C
• Appearance: /
• Density: 1.69g/cm³
• PKA: -3.02±0.44(Predicted)
• CAS DataBase Reference: 2-Pyridinol, 3,5-dinitro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinol, 3,5-dinitro-(222548-10-9)
• EPA Substance Registry System: 2-Pyridinol, 3,5-dinitro-(222548-10-9)

Safety Data

• Hazardous Substances Data: 222548-10-9(Hazardous Substances Data)

Usage

General Description

2-Pyridinol, 3,5-dinitro- is a chemical compound that is commonly used in the manufacturing of pesticides and herbicides. It is a yellow crystalline solid that is soluble in organic solvents. 2-Pyridinol, 3,5-dinitro- is used as an intermediate in the production of various agricultural chemicals and can also be used as a building block in the synthesis of pharmaceuticals and other industrial chemicals. Its dinitro-substituted pyridinol structure gives it unique properties and makes it valuable in a range of applications in the chemical industry. However, it is important to handle this chemical with care as it has been classified as a hazardous substance due to its potential for acute toxicity.

Upstream product

• 142-08-5 2-Pyridone 
• 5418-51-9 5-nitro-2-hydroxypyridine 
• 6332-56-5 2-hydroxy-3-nitropyridine 
• 2578-45-2 2-chloro-3,5-dinitropyridine 
• 142-08-5 2-hydroxypyridin 
• 1824-81-3 2-Amino-6-methylpyridine 
• 6635-31-0 6-hydroxy-5-nitronicotinic acid 
• 7697-37-2 nitric acid 
• 13472-80-5 2-hydroxy-3,5-diiodopyridine 
• 25864-34-0 2-amino-3,5-dinitro-6-methylpyridine 
• 5418-51-9 5-nitro-2-pyridone 

Relevant articles and documents

Studies on hydrogen exchange. IX. Electrophilic deuteration of 2-pyridinol, 2-quinolinol, and 1-isoquinolinol.

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Amino- and hydroxymethylation of hydride adducts of 2-hydroxy-3,5- dinitropyridine

A series of 1,5-dinitro-3,3-diazabicyclo[3.3.1]nonan-2-one derivatives has been synthesized by Mannich condensation of the hydride adduct of 2-hydroxy-3,5-dinitropyridine with formaldehyde and primary amines. The structure of the obtained compounds was proved by NMR spectroscopy.

Reactivity of heterocyclic compounds in nitration. 8. Nitration of 3-hydroxypyridine and its substituted forms

Nitration of 3-hydroxypyridine and its substituted forms has been studied under various conditions. It is shown that, depending on the reaction temperature and the nitrating agent, the end products of the synthesis can be 3-hydroxy-2,6-dinitropyridine or 3-hydroxy-2,4,6-trinitropyridine. The possibility of substitutional nitration of iodine derivatives of 2- and 3-hydroxypyridine is demonstrated. 1999 Kluwer Academic/Plenum Publishers.

THE REACTIVITY OF SOME PRIMARY AMINES IN SN2Ar REACTIONS WITH 2-CHLORO-3,5-DINITROPYRIDINE

Rate constants for SN2Ar reactions of 2-chloro-3,5-dinitropyridine (1) with butylamine, glycine, glycylglycine and ethylenediamine monohydrochloride, in water at 1.0 mol dm-3 constant ionic strength and 25 deg C, have been determined.The Broensted β coefficient is 0.51.The reactivities of 1 and 2-chloro-1-methylpyridinium ion (2) with these primary amines were compared using a derived Edwards equation.One could infer that 2 tends to undergo more charge interaction than 1 because of the quaternary nitrogen of the pyridinium ring of 2.A coordination of the substrates, 1, 2 and 4-chloro-1-methylpyridinium ion (3) dependent on the degree of hardness and softness is presented.