2226-83-7Relevant articles and documents
Further syntheses in the study of structure-activity relationships of neuropharmacologically active amino acids.
Cheah,Watkins
, p. 821 - 824 (1965)
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2-Carboxytetrahydroquinolines. Conformational and Stereochemical Requirements for Antagonism of the Glycine Site on the NMDA Receptor
Carling, Robert W.,Leeson, Paul D.,Moseley, Angela M.,Baker, Raymond,Foster, Alan C.,et al.
, p. 1942 - 1953 (2007/10/02)
2-Carboxy-1,2,3,4-tetrahydroquinoline derivatives, derived from kynurenic acid, have been synthesized and evaluated for in vitro antagonist activity at the glycine site on the NMDA receptor. 2,3-Dihydrokynurenic acids show reduced potency relative to the