222631-56-3

Upstream product

• 13162-26-0 2,4-dichloro-6-methyl-5-nitropyrimidine 
• 30958-38-4 2,4-bis-O-benzyl-6-methyl-5-nitro pyrimidine 
• 16632-21-6 5-nitro-6-methyluracil 

Downstream Products

• 1446175-09-2 2,4-bis-benzyloxy-5-N-boc-7-iodopyrrolo[3,2-d]pyrimidine 
• 1446175-08-1 2,4-bis-benzyloxy-5-N-(toluene-4-sulfonyl)-7-iodopyrrolo-[3,2-d]pyrimidine 
• 1446175-07-0 2,4-bis-benzyloxy-5-N-(benzyloxymethyl)-7-iodopyrrolo-[3,2-d]pyrimidine 
• 1446175-06-9 2,4-bis-benzyloxy-5-N-benzyl-7-iodo-pyrrolo[3,2-d]-pyrimidine 
• 1446175-05-8 2,4-bis-benzyloxy-5-N-(tert-butyldimethylsilyl)-7-iodopyrrolo[3,2-d]pyrimidine 
• 1446175-04-7 7-iodo-2,4-bis-benzyloxy-5H-pyrrolo[3,2-d]-pyrimidine 
• 1446175-16-1 1′-β-[7-(5-benzylpyrrolo[3,2-d]pyrimidin-2,4-dione)]-2′-deoxyribofuranose 
• 1446175-13-8 1′-β-[7-(2,4-bis-benzyloxy-5-benzyloxymethypyrrolo[3,2-d]pyrimidine)]-2′-deoxyribofuranose 
• 1446175-15-0 1′-β-[7-(2,4-bis-benzyloxy-5-N-benzylpyrrolo[3,2-d]-pyrimidine)]-2′-deoxyribofuranose 
• 1446175-14-9 1′-β-[7-(2,4-bis-benzyloxy-5H-pyrrolo[3,2-d]pyrimidine)]-2′-deoxyribofuranose 
• 1446175-10-5 2,4-bis-benzyloxy-5-N-benzyloxymethy-7-(β-D-glycero-pentofuran-3′-ulos-1′-yl)pyrrolo[3,2-d]pyrimidine 
• 1446175-12-7 2,4-bis-benzyloxy-5-N-benzyl-7-(β-D-glycero-pentofuran-3′-ulos-1′-yl)pyrrolo[3,2-d]pyrimidine 
• 1446175-11-6 2,4-bis-benzyloxy-5H-7-(β-D-glycero-pentofuran-3′-ulos-1′-yl)pyrrolo[3,2-d]pyrimidine 
• 1446175-17-2 C₄₉H₄₉N₃O₆Si 

Relevant academic research and scientific papers

THIENO- AND PYRROLOPYRIMIDINE ANALOGUES AS ANTICANCER AGENTS AND METHODS OF USE THEREOF

The present invention provides for the design and synthesis of halogenated thieno- and pyrrolopyrimidine compounds that exhibit cancer proliferation inhibitory activity and the use thereof for cancer treatment.

Antiproliferative activities of halogenated pyrrolo[3,2-d]pyrimidines

In vitro evaluation of the halogenated pyrrolo[3,2-d]pyrimidines identified antiproliferative activities in compounds 1 and 2 against four different cancer cell lines. Upon screening of a series of pyrrolo[3,2-d]pyrimidines, the 2,4-Cl compound 1 was foun

Addition of lithiated 9-deazapurine derivatives to a carbohydrate cyclic imine: Convergent synthesis of the aza-C-nucleoside immucillins

Means have been developed for the synthesis and addition of 9-deaza-9-lithiopurine derivatives to the carbohydrate-derived cyclic imine 6 in facile convergent syntheses of biologically active aza-C-nucleosides.