22280-95-1Relevant articles and documents
A concise synthesis of (±)-methoxyfumimycin ethyl ester
Zhou, Zhiwang,Hu, Yu,Wang, Bin,He, Xiaoru,Ren, Gang,Feng, Lihua
, p. 378 - 380 (2014)
The protecting-group-free synthesis of (±)-methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase (PDF) inhibitor, is reported. The synthetic approach features a tandem Friedel-Crafts alkylation/lactonisation access as a key reaction to g
Design, synthesis, characterization, and anticancer activity of a novel series of O-substituted chalcone derivatives
Ngameni, Bathélémy,Cedric, Kamdoum,Mbaveng, Armelle T.,Erdo?an, Musa,Simo, Ingrid,Kuete, Victor,Da?tan, Arif
, (2021)
A new series of O-substituted chalcone derivatives bearing an/a allyl-, prenyl- or propargyl-substituent at different positions of rings A and B and their derivatives as drug leads, was designed, synthesized, and characterized. The chalcone derivatives we
Introducing the Tishchenko reaction into sustainable polymer chemistry
Ren, Tianhua,Chen, Qin,Zhao, Changbo,Zheng, Qiang,Xie, Haibo,North, Michael
, p. 1542 - 1547 (2020)
Taking advantage of the structural characteristics of lignin-derived phenolic compounds, a combination of the Williamson and Tishchenko reactions produced a series of new α,ω-diene functionalized carboxylic ester monomers from both petrochemical and renewable resources, which were applicable in subsequent thiol-ene click and acyclic diene metathesis (ADMET) polymerizations, providing a series of poly(thioether esters) and unsaturated aromatic-aliphatic polyesters with high molecular weights.
Synthesis of the intermediate for fumimycin: A natural peptide deformylase inhibitor
Zhou, Zhi-Wang,Li, Wei-Chao,Hu, Yu,Wang, Bin,Ren, Gang,Feng, Li-Hua
, p. 3049 - 3054 (2013)
Synthetic efforts toward the potential bacterial peptide deformylase inhibitor fumimycin are reported. The synthetic approach features a tandem Friedel-Crafts alkylation/lactonization access as key reaction to the α, α-disubstituted amino acid unit, and r
Chemoselective and ligand-free aerobic oxidation of benzylic alcohols to carbonyl compounds using alumina-supported mesoporous nickel nanoparticle as an efficient recyclable heterogeneous catalyst
Das, Asit Kumar,Nandy, Sneha,Bhar, Sanjay
, (2021/05/10)
An economically efficient and operationally simple ligand-free protocol for the chemoselective oxidation of benzylic alcohols to carbonyl compounds has been developed using alumina-supported nickel nanoparticles as a stable recyclable heterogeneous catalyst along with potassium tert-butoxide in the presence of aerial oxygen as an eco-friendly oxidant. The aliphatic alcohols remained unaffected under the present condition. Excellent chemoselectivity has also been demonstrated through intermolecular and intramolecular competition experiments. This protocol accommodates a diverse range of substituents with the tolerance of various sensitive moieties during the reaction. The catalyst could be recovered by filtration and reused consecutively without any significant loss in the catalytic activity. Moreover, the heterogeneity of the catalyst has also been established by the “hot filtration method (Sheldon's test)”.