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4-(ALLYLOXY)-3-METHOXYBENZALDEHYDE is a chemical compound with a molecular formula C11H12O3. It is a benzaldehyde derivative that contains an allyloxy group and a methoxy group, both attached to the benzene ring. 4-(ALLYLOXY)-3-METHOXYBENZALDEHYDE has a yellowish to brownish appearance and a strong, sweet almond-like odor. It is used as a versatile building block in organic synthesis and is commonly used as a reagent in organic reactions to introduce the allyloxy and methoxy groups into different molecules.
Used in Pharmaceutical Industry:
4-(ALLYLOXY)-3-METHOXYBENZALDEHYDE is used as a building block for the synthesis of various pharmaceutical compounds due to its ability to introduce the allyloxy and methoxy groups into different molecules.
Used in Perfumery Industry:
4-(ALLYLOXY)-3-METHOXYBENZALDEHYDE is used as a fragrance ingredient for its strong, sweet almond-like odor.
It is important to handle this chemical with care, as it can be a skin and eye irritant.

22280-95-1

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22280-95-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 22280-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,2,8 and 0 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 22280-95:
(7*2)+(6*2)+(5*2)+(4*8)+(3*0)+(2*9)+(1*5)=91
91 % 10 = 1
So 22280-95-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O3/c1-3-6-14-10-5-4-9(8-12)7-11(10)13-2/h3-5,7-8H,1,6H2,2H3

22280-95-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-methoxy-4-prop-2-enoxybenzaldehyde

1.2 Other means of identification

Product number -
Other names O-allylvanillin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:22280-95-1 SDS

22280-95-1Relevant academic research and scientific papers

A concise synthesis of (±)-methoxyfumimycin ethyl ester

Zhou, Zhiwang,Hu, Yu,Wang, Bin,He, Xiaoru,Ren, Gang,Feng, Lihua

, p. 378 - 380 (2014)

The protecting-group-free synthesis of (±)-methoxyfumimycin ethyl ester, a potential bacterial peptide deformylase (PDF) inhibitor, is reported. The synthetic approach features a tandem Friedel-Crafts alkylation/lactonisation access as a key reaction to g

Synthesis and structural characterization of novel O-substituted phenolic and chalcone derivatives with antioxidant activity

Ngameni, Bathélémy,Erdo?an, Musa,Kuete, Victor,Dalk?l??, Erdin,Ngadjui, Bonaventure T,Da?tan, Arif

, p. 159 - 165 (2021)

A series of novel 4-O-alkyltriazolylphenolic derivatives is first synthesized with good to excellent yields via the click reaction of 3-methoxy-4-O-propargylbenzaldehyde or 3-allyl-4-O-propargylacetophenone and aromatic azide derivatives. Next, the chalco

Design, synthesis, characterization, and anticancer activity of a novel series of O-substituted chalcone derivatives

Ngameni, Bathélémy,Cedric, Kamdoum,Mbaveng, Armelle T.,Erdo?an, Musa,Simo, Ingrid,Kuete, Victor,Da?tan, Arif

, (2021)

A new series of O-substituted chalcone derivatives bearing an/a allyl-, prenyl- or propargyl-substituent at different positions of rings A and B and their derivatives as drug leads, was designed, synthesized, and characterized. The chalcone derivatives we

Concise and Convergent Enantioselective Total Syntheses of (+)-and (-)-Fumimycin

Retini, Michele,Bartolucci, Silvia,Bartoccini, Francesca,Mari, Michele,Piersanti, Giovanni

, p. 12221 - 12227 (2019)

The concise and convergent total syntheses of (+)-and (-)-Fumimycin have been achieved by taking advantage of strategies for the asymmetric aza-Friedel-Crafts reaction of a highly substituted hydroquinone and N-fumaryl ketimine generated from the correspo

Introducing the Tishchenko reaction into sustainable polymer chemistry

Ren, Tianhua,Chen, Qin,Zhao, Changbo,Zheng, Qiang,Xie, Haibo,North, Michael

, p. 1542 - 1547 (2020)

Taking advantage of the structural characteristics of lignin-derived phenolic compounds, a combination of the Williamson and Tishchenko reactions produced a series of new α,ω-diene functionalized carboxylic ester monomers from both petrochemical and renewable resources, which were applicable in subsequent thiol-ene click and acyclic diene metathesis (ADMET) polymerizations, providing a series of poly(thioether esters) and unsaturated aromatic-aliphatic polyesters with high molecular weights.

Synthesis of a Novel calix[4]resorcinarene-Chitosan hybrid

Santoso, Prio,Anwar, Chairil,Jumina,Siswanta, Dwi,Suharso,Ohto, Keisuke

, p. 30 - 37 (2018)

Synthesis of a novel calix[4]resorcinarene-chitosan hybrid using vanillin as raw material has been conducted. The synthesis was carried out in four steps i.e. (1) allylation of vanillin, (2) HCl-catalyzed condensation allyl vanillin with resorcinol, (3) c

Synthesis of the intermediate for fumimycin: A natural peptide deformylase inhibitor

Zhou, Zhi-Wang,Li, Wei-Chao,Hu, Yu,Wang, Bin,Ren, Gang,Feng, Li-Hua

, p. 3049 - 3054 (2013)

Synthetic efforts toward the potential bacterial peptide deformylase inhibitor fumimycin are reported. The synthetic approach features a tandem Friedel-Crafts alkylation/lactonization access as key reaction to the α, α-disubstituted amino acid unit, and r

Iodine-DMSO catalyzed chemoselective oxidative aromatization and deallylation, nondeallylation of aryl allyl ether of tetrahydro-β-carboline

Gaikwad, Sunil V.,Gaikwad, Milind V.,Lokhande, Pradeep D.

supporting information, p. 1408 - 1414 (2021/04/26)

We have developed a simple method for the chemoselective aromatization of tetrahydro-β-carboline with selective nondeallylation O-allyl groups in the presence of iodine (100 mol %) in dimethyl sulfoxide/H2O2. A convergent approach toward the oxidative aromatization with selective deallylation (deprotection) of O-allyl-tetrahydro-β-carboline using iodine in dimethyl sulfoxide/HCl has been described. The present protocol contains cheap catalyst, easy work up, normal reaction conditions, and high selectivity.

Chemoselective and ligand-free aerobic oxidation of benzylic alcohols to carbonyl compounds using alumina-supported mesoporous nickel nanoparticle as an efficient recyclable heterogeneous catalyst

Das, Asit Kumar,Nandy, Sneha,Bhar, Sanjay

, (2021/05/10)

An economically efficient and operationally simple ligand-free protocol for the chemoselective oxidation of benzylic alcohols to carbonyl compounds has been developed using alumina-supported nickel nanoparticles as a stable recyclable heterogeneous catalyst along with potassium tert-butoxide in the presence of aerial oxygen as an eco-friendly oxidant. The aliphatic alcohols remained unaffected under the present condition. Excellent chemoselectivity has also been demonstrated through intermolecular and intramolecular competition experiments. This protocol accommodates a diverse range of substituents with the tolerance of various sensitive moieties during the reaction. The catalyst could be recovered by filtration and reused consecutively without any significant loss in the catalytic activity. Moreover, the heterogeneity of the catalyst has also been established by the “hot filtration method (Sheldon's test)”.

Preparation, characterization, antioxidant evaluation of new curcumin derivatives and effects of forming HSA-bound nanoparticles on the stability and activity

Gao, Feng,Guo, Na,Hao, Tiantian,Wang, Kai,Wang, Pingxi,Yang, Shuyan,Yu, Peng,Zhang, Shutong,Zhao, Yufan

, (2020/09/16)

Curcumin (CCM) is a well-known active component, which has been studied extensively in food and medicine field since it showed various activities. However, some serious issues limit its application, for example, the extremely low solubility, stability and

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