86534-11-4Relevant articles and documents
Synthesis of tri-arylated cyclotriveratrilenes with ortho- and meta-extended functionality
Ito, Kouhei,Schramm, Michael P.,Kanaura, Mao,Ide, Masataka,Endo, Naoki,Iwasawa, Tetsuo
, p. 233 - 236 (2016)
Aromatic nucleophilic substitution reaction between cyclotriguaiacylene and ortho- or meta-functionalized fluoroarenes affords a series of ortho- or meta-extended cyclotriveratrilene (CTV) cavitands. Further transformation of the functional groups into NH
A tris(benzyltriazolemethyl)amine-based cage as a CuAAC ligand tolerant to exogeneous bulky nucleophiles
Qiu, Gege,Nava, Paola,Martinez, Alexandre,Colomban, Cédric
supporting information, p. 2281 - 2284 (2021/03/09)
The archetypal tris(benzyltriazolemethyl)amine (TBTA) ligand was equipped with a bowl-shaped cap in the cage Hm-TBTA. Hm-TBTA accelerates CuAAC reactions without suffering from product inhibition. Furthermore, this shielded ligand efficiently protects the
Controlled Reduction of Carboxamides to Alcohols or Amines by Zinc Hydrides
Ong, Derek Yiren,Yen, Zhihao,Yoshii, Asami,Revillo Imbernon, Julia,Takita, Ryo,Chiba, Shunsuke
supporting information, p. 4992 - 4997 (2019/03/13)
New protocols for controlled reduction of carboxamides to either alcohols or amines were established using a combination of sodium hydride (NaH) and zinc halides (ZnX2). Use of a different halide on ZnX2 dictates the selectivity, wherein the NaH-ZnI2 system delivers alcohols and NaH-ZnCl2 gives amines. Extensive mechanistic studies by experimental and theoretical approaches imply that polymeric zinc hydride (ZnH2)∞ is responsible for alcohol formation, whereas dimeric zinc chloride hydride (H?Zn?Cl)2 is the key species for the production of amines.