222843-40-5Relevant academic research and scientific papers
Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (±)-makaluvamine F using hypervalent iodine(III)-induced reactions
Kita, Yasuyuki,Egi, Masahiro,Tohma, Hirofumi
, p. 143 - 144 (2007/10/03)
The first total synthesis of potent cytotoxic makaluvamine F 1, a sulfur-containing pyrroloiminoquinone marine product, has been accomplished using hypervalent iodine(III)-induced reactions.
Development of novel reactions using hypervalent iodine(III) reagents: Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (±)-makaluvamine F
Kita, Yasuyuki,Egi, Masahiro,Takada, Takeshi,Tohma, Hirofumi
, p. 885 - 897 (2007/10/03)
Novel and efficient intramolecular nucleophilic substitution reactions of phenol ethers using activated hypervalent iodine species have been developed and their application to the total synthesis of strongly cytotoxic makaluvamine F (1), a member of sulfur-containing pyrroloiminoquinone marine products, is described.
