222843-69-8

Upstream product

• 101111-25-5 methyl 2-(4-(benzyloxy)-3-bromophenyl)acetate 
• 501-94-0 p-hydroxyphenethyl alcohol 
• 100-44-7 benzyl chloride 
• 196081-78-4 3-bromo-4-hydroxyphenylethyl alcohol 
• 34918-57-5 methyl 3-bromo-4-hydroxyphenylacetate 
• 14199-15-6 Methyl 4-hydroxyphenylacetate 
• 234757-51-8 ethyl 2-(4-(benzyloxy)-3-bromophenyl)acetate 

Downstream Products

• 1401074-00-7 2-(4-benzyloxy-3-methoxyphenyl)ethyl β-D-glucopyranoside 
• 1401074-01-8 2-(4-benzyloxy-3-methoxyphenyl)ethyl β-D-galactopyranoside 
• 1401074-04-1 2-(4-benzyloxy-3-ethoxyphenyl)ethyl β-D-glucopyranoside 
• 1401074-05-2 2-(4-benzyloxy-3-ethoxyphenyl)ethyl β-D-galactopyranoside 
• 850232-24-5 2-(4-hydroxy-3-methoxyphenyl)ethyl β-D-galactopyranoside 
• 1350703-40-0 2-(4-hydroxy-3-ethoxyphenyl)ethyl β-D-glucopyranoside 
• 1350703-41-1 2-(4-hydroxy-3-ethoxyphenyl)ethyl β-D-galactopyranoside 
• 64881-05-6 1-<4-(benzyloxy)-3-methoxyphenyl>ethan-2-ol 
• 1401073-99-1 2-(4-benzyloxy-3-ethoxyphenyl)ethanol 
• 222843-62-1 Benzyl 2-(4-benzyloxy-3-bromophenyl)ethyl sulfide 
• 222843-40-5 6-Benzyloxy-5-bromo-2,3-dihydrobenzothiophene 
• 234757-52-9 2-(4-Benzyloxy-3-bromophenyl)-1-iodoethane 

Relevant academic research and scientific papers

Synthesis of salidroside analogues and their ability of DPPH radical scavenging activity

Salidroside is a phenylpropanoid glycoside isolated from Rhodiolarosea L., a traditional Chinese medicinal plant, and has displayed a broad spectrum of pharmacological properties. In this paper, about 22 novel glycosides have been synthesized and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenge activity of each glycoside has been evaluated. 2-(3,4,5-Trihydroxyphenyl)ethyl β-D-galactopyranoside and 3-(3,4,5-trihydroxyphenyl)propyl β-D-glucopyranoside exhibit significant activity prior to salidroside and Vitamin C with EC50 values of 35.85 μM and 36.71 μM, respectively. The results indicate that the phenolic hydroxyl group of these compounds is important for radical scavenging activity and phenyl ring substitution by electron-donating substituents lead to increased antioxidant activity.

Development of novel reactions using hypervalent iodine(III) reagents: Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (±)-makaluvamine F

Novel and efficient intramolecular nucleophilic substitution reactions of phenol ethers using activated hypervalent iodine species have been developed and their application to the total synthesis of strongly cytotoxic makaluvamine F (1), a member of sulfur-containing pyrroloiminoquinone marine products, is described.

Total synthesis of sulfur-containing pyrroloiminoquinone marine product, (±)-makaluvamine F using hypervalent iodine(III)-induced reactions

The first total synthesis of potent cytotoxic makaluvamine F 1, a sulfur-containing pyrroloiminoquinone marine product, has been accomplished using hypervalent iodine(III)-induced reactions.