222992-24-7Relevant academic research and scientific papers
Solid-phase synthesis of deoxynucleic guanidine (DNG) oligomersand melting point and circular dichroism analysis of binding fidelity of octameric thymidyl oligomers with DNA oligomers
Linkletter, Barry A.,Szabo, Istvan E.,Bruice, Thomas C.
, p. 3888 - 3896 (1999)
A practical solid-phase synthesis of deoxynucleic guanidine (DNG), a positively charged DNA backbone analogue, is reported. The nucleoside coupling step in the solid-phase synthesis of DNG involves the attack of a terminal 3′-amine upon an electronically
