22324-44-3

Usage

Uses

1. Used in Pharmaceutical Research:
Palustrine is used as a research compound for its potential pharmaceutical applications. The expression is: palustrine is used as a research compound for [investigating its properties and potential applications in the pharmaceutical industry].
2. Used in Toxicology Studies:
Palustrine is used as a toxicological agent for studying its effects on cattle and other animals. The expression is: palustrine is used as a toxicological agent for [studying its effects on cattle and understanding the causes of poisoning].
3. Used in Structural Chemistry:
Palustrine is used as a subject for structural chemistry studies to determine its complete structure and potentially discover new derivatives or related compounds. The expression is: palustrine is used as a subject for structural chemistry studies for [determining its complete structure and exploring related compounds].

References

Glet, Gutschmidt, Glet., Zeit. Physiol. Chem., 244, 229 (1936) Karrer, Eugster., Helv. Chim. Acta., 31, 1062 (1948) Eugster.,Griot, Karrer., ibid, 36, 1387 (1953) Structure: Mayer et al., Helv. Chim. Acta, 51,661 (1968)

InChI:InChI=1/C17H31N3O2/c1-2-16(21)15-8-5-7-14-13-17(22)19-11-4-3-9-18-10-6-12-20(14)15/h5,7,14-16,18,21H,2-4,6,8-13H2,1H3,(H,19,22)/t14-,15+,16+/m1/s1

Upstream product

• 94608-04-5 N-{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-N-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-4-methyl-benzenesulfonamide 
• 94608-05-6 N-{4-[{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-(toluene-4-sulfonyl)-amino]-butyl}-2,2,2-trifluoro-acetamide 
• 94608-06-7 [(2R,6R)-6-((R)-1-Methoxymethoxy-propyl)-1-(3-{(toluene-4-sulfonyl)-[4-(2,2,2-trifluoro-acetylamino)-butyl]-amino}-propyl)-1,2,5,6-tetrahydro-pyridin-2-yl]-acetic acid methyl ester 
• 94608-00-1 (2R,3S,6R)-2-(2,2-Diethoxy-ethyl)-6-((R)-1-methoxymethoxy-propyl)-3-(2,2,2-trichloro-acetylamino)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94607-94-0 (2R,3S,6S)-3-Benzoyloxy-6-(2,2-diethoxy-ethyl)-2-((S)-1-hydroxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94607-97-3 N-{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-3-oxo-propyl}-4-methyl-benzenesulfonamide 
• 94607-98-4 N-{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-4-methyl-benzenesulfonamide 
• 94608-01-2 (2R,6R)-2-(2,2-Diethoxy-ethyl)-3-dimethylamino-6-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94607-95-1 (2R,3R,6R)-6-(2,2-Diethoxy-ethyl)-3-hydroxy-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94608-02-3 (2R,3S,6R)-2-(2,2-Diethoxy-ethyl)-3-dimethylamino-6-((R)-1-methoxymethoxy-propyl)-piperidine-1-carboxylic acid benzyl ester 
• 94607-96-2 (2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 79477-05-7 (2R,3S,6S)-6-(2,2-Diethoxy-ethyl)-3-hydroxy-2-vinyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94656-49-2 (4R,15aR)-4-((R)-1-Hydroxy-propyl)-8-(toluene-4-sulfonyl)-3,4,6,7,8,9,10,11,12,13,15,15a-dodecahydro-5H-4a,8,13-triaza-benzocyclotridecen-14-one 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (+/-)-PALUSTRINE AND STRUCTURE REVISION

(+/-)-Palustrine (1a) was totally synthesized in a stereoselective manner using a 1,3-transposition reaction of the hetero atom of 5 as a key step.This study establishes the revised structures (1a and 1b) for palustrine and palustridine. KEYWORDS --- palu