94607-97-3

Upstream product

• 61341-03-5 N-(toluene-4-sulfonyl)-β-alanyl chloride 
• 94608-01-2 (2R,6R)-2-(2,2-Diethoxy-ethyl)-3-dimethylamino-6-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94608-00-1 (2R,3S,6R)-2-(2,2-Diethoxy-ethyl)-6-((R)-1-methoxymethoxy-propyl)-3-(2,2,2-trichloro-acetylamino)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94607-94-0 (2R,3S,6S)-3-Benzoyloxy-6-(2,2-diethoxy-ethyl)-2-((S)-1-hydroxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94607-95-1 (2R,3R,6R)-6-(2,2-Diethoxy-ethyl)-3-hydroxy-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 94608-02-3 (2R,3S,6R)-2-(2,2-Diethoxy-ethyl)-3-dimethylamino-6-((R)-1-methoxymethoxy-propyl)-piperidine-1-carboxylic acid benzyl ester 
• 94607-96-2 (2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 79477-05-7 (2R,3S,6S)-6-(2,2-Diethoxy-ethyl)-3-hydroxy-2-vinyl-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 

Downstream Products

• 94607-98-4 N-{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-4-methyl-benzenesulfonamide 
• 22324-44-3 (+/-)-palustrine 
• 94656-49-2 (4R,15aR)-4-((R)-1-Hydroxy-propyl)-8-(toluene-4-sulfonyl)-3,4,6,7,8,9,10,11,12,13,15,15a-dodecahydro-5H-4a,8,13-triaza-benzocyclotridecen-14-one 
• 94608-06-7 [(2R,6R)-6-((R)-1-Methoxymethoxy-propyl)-1-(3-{(toluene-4-sulfonyl)-[4-(2,2,2-trifluoro-acetylamino)-butyl]-amino}-propyl)-1,2,5,6-tetrahydro-pyridin-2-yl]-acetic acid methyl ester 
• 94608-05-6 N-{4-[{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-(toluene-4-sulfonyl)-amino]-butyl}-2,2,2-trifluoro-acetamide 
• 94608-04-5 N-{3-[(2R,6R)-6-(2,2-Diethoxy-ethyl)-2-((R)-1-methoxymethoxy-propyl)-3,6-dihydro-2H-pyridin-1-yl]-propyl}-N-[4-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-butyl]-4-methyl-benzenesulfonamide 

Relevant academic research and scientific papers

TOTAL SYNTHESIS OF (+/-)-PALUSTRINE AND STRUCTURE REVISION

(+/-)-Palustrine (1a) was totally synthesized in a stereoselective manner using a 1,3-transposition reaction of the hetero atom of 5 as a key step.This study establishes the revised structures (1a and 1b) for palustrine and palustridine. KEYWORDS --- palu