223253-85-8

Basic information

• Product Name: 1-(4-chloromethyl-oxazol-2-ylmethyl)-4-(2-isopropoxy-phenyl)-piperazine
• Synonyms: 1-(4-chloromethyl-oxazol-2-ylmethyl)-4-(2-isopropoxy-phenyl)-piperazine
• CAS NO: 223253-85-8
• Molecular Weight: 349.86
• Mol File: 223253-85-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-chloromethyl-oxazol-2-ylmethyl)-4-(2-isopropoxy-phenyl)-piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chloromethyl-oxazol-2-ylmethyl)-4-(2-isopropoxy-phenyl)-piperazine(223253-85-8)
• EPA Substance Registry System: 1-(4-chloromethyl-oxazol-2-ylmethyl)-4-(2-isopropoxy-phenyl)-piperazine(223253-85-8)

Safety Data

• Hazardous Substances Data: 223253-85-8(Hazardous Substances Data)

Upstream product

• 483987-66-2 2-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-oxazole-4-carboxylic acid ethyl ester 
• 142841-00-7 2-[bromomethyl]-4-oxazolecarboxylic acid ethyl ester 
• 10200-43-8 2-methyl-4-carbethoxy-1,3-oxazole 
• 483987-67-3 {2-[4-(2-isopropoxy-phenyl)-piperazin-1-ylmethyl]-oxazol-4-yl}-methanol 

Relevant articles and documents

Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists.

Antagonists of the alpha(1)-adrenergic receptors (alpha(1)-ARs) are useful for the treatment of benign prostatic hyperplasia. A series of potent and subtype-selective alpha(1a)-AR antagonists has been synthesized, displaying in vitro binding affinity in the low the nanomolar range.