483987-66-2Relevant academic research and scientific papers
Arylpiperazine substituted heterocycles as selective alpha(1a) adrenergic antagonists.
Khatuya, Haripada,Hutchings, Richard H,Kuo, Gee-Hong,Pulito, Virginia L,Jolliffe, Linda K,Li, Xiaobing,Murray, William V
, p. 2443 - 2446 (2007/10/03)
Antagonists of the alpha(1)-adrenergic receptors (alpha(1)-ARs) are useful for the treatment of benign prostatic hyperplasia. A series of potent and subtype-selective alpha(1a)-AR antagonists has been synthesized, displaying in vitro binding affinity in the low the nanomolar range.
