223261-80-1

Upstream product

• 67-68-5 dimethyl sulfoxide 
• 223261-77-6 C-(2,3,4,6-tetra-O-acetyl-1-bromo-1-deoxy-β-D-glucopyranosyl)formamide 
• 82469-74-7 2,3,4,6-tetra-O-acetyl-1-deoxy-1-bromo-β-D-glycopyranosyl cyanide 
• 333-20-0 potassium thioacyanate 
• 67-64-1 acetone 
• 3315-16-0 silver cyanate 
• 1701-93-5 silver thiocyanate 

Relevant academic research and scientific papers

Novel glycosylidene-spiro-heterocycles from unprecedented solvent incorporation in Koenigs-Knorr-like reactions of C-(1-bromo-1-deoxy-β-D-glycopyranosyl)formamides

The title compounds give glycopyranosylidene-spiro-dioxolanes 3 and 4 in acetone and C-(1-methylsulfanylmethoxy-α-D-glycopyranosyl)formamides 5 in DMSO in the presence of Ag2CO3 and AgF, respectively.

Synthesis of and a comparative study on the inhibition of muscle and liver glycogen phosphorylases by epimeric pairs of D-gluco- and D-xylopyranosylidene-spiro-(thio)hydantoins and N-(D-glucopyranosyl) amides

D-Gluco- and D-xylopyranosylidene-spiro-hydantoins and -thiohydantoins were prepared from the parent sugars in a six-step, highly chemo-, regio-, and stereoselective procedure. In the key step of the syntheses C-(1-bromo-1-deoxy-β-D-glycopyranosyl)formami

Efficient inhibition of muscle and liver glycogen phosphorylases by a new glucopyranosylidene-spiro-thiohydantoin

Reaction of C-(1-bromo-1-deoxy-β-D-glucopyranosyl)formamide 2 with thiocyanate ions was the key step of a short synthesis of D- glucopyranosylidene-spiro-thiohydantoin 7 which proved to be a potent inhibitor of muscle and liver glycogen phosphorylases.