22333-84-2Relevant academic research and scientific papers
BIDESMOSIDIC BETULIN AND BETULINIC ACID DERIVATIVES AND USES THEREOF AS ANTITUMOR AGENTS
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Page/Page column 39, (2010/04/06)
The instant application is directed to bidesmosidic betulin and betulinic acid saponin derivatives of formula (I), and use thereof as antitumor agents. In particular, said compounds are effective in treating lung carcinomas, colorectal adenocarcinomas, br
Synthesis and cytotoxicity of bidesmosidic betulin and betulinic acid saponins
Gauthier, Charles,Legault, Jean,Lavoie, Serge,Rondeau, Simon,Tremblay, Samuel,Pichette, Andre
experimental part, p. 72 - 81 (2009/05/26)
The naturally occurring cytotoxic saponin 28-O-β-D- glucopyranosylbetulinic acid 3β-O-α-L-arabinopyranoside (3) was easily synthesized along with seven bidesmosidic saponins starting from the lupane-type triterpenoids betulin (1) and betulinic acid (2). A
