223449-74-9

Basic information

• Product Name: [3-(4-tert-butoxycarbonylamino-butylcarbamoyl)-5-(dimethoxy-phosphorylmethyl)-benzyl]-phosphonic acid dimethyl ester
• Synonyms: [3-(4-tert-butoxycarbonylamino-butylcarbamoyl)-5-(dimethoxy-phosphorylmethyl)-benzyl]-phosphonic acid dimethyl ester
• CAS NO: 223449-74-9
• Molecular Weight: 536.499
• Mol File: 223449-74-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [3-(4-tert-butoxycarbonylamino-butylcarbamoyl)-5-(dimethoxy-phosphorylmethyl)-benzyl]-phosphonic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-tert-butoxycarbonylamino-butylcarbamoyl)-5-(dimethoxy-phosphorylmethyl)-benzyl]-phosphonic acid dimethyl ester(223449-74-9)
• EPA Substance Registry System: [3-(4-tert-butoxycarbonylamino-butylcarbamoyl)-5-(dimethoxy-phosphorylmethyl)-benzyl]-phosphonic acid dimethyl ester(223449-74-9)

Safety Data

• Hazardous Substances Data: 223449-74-9(Hazardous Substances Data)

Upstream product

• 68076-36-8 1-amino-4-[(tert-butyloxycarbonyl)amino]butane 
• 223449-19-2 5-carboxy-m-xylylenebisphosphonic acid tetramethyl ester 
• 223449-25-0 5-methoxycarbonyl-m-xylylene bisphosphonic acid tetramethyl ester 
• 94111-75-8 3,5-bis(bromomethyl)benzoic acid 
• 123065-60-1 3,5-bis(hydroxylmethyl)benzoic acid 
• 38588-64-6 3,5-bis(methoxycarbonyl)benzoic acid 

Relevant articles and documents

Synthesis of 3,5-bis(phosphonomethyl)benzoic acid and its application as a metal oxide surface bivalent anchor

A protected form of 3,5-bis(phosphonomethyl)benzoic acid (Bpb-OH), a metal oxide surface bivalent anchor, has been synthesized, coupled to an amine functionality, deprotected, and shown to bind to metal oxide surfaces. The protected anchor, 3,5-bis(dimethoxyphosphinylmethyl)benzoic acid (Me4Bpb-OH) was synthesized in 23% yield over four steps, coupled to a proline-chromophore, deprotected with a solution of iodotrimethylsilane (TMSI) in acetonitrile and adsorbed to Tin(IV)-doped indium oxide and nanocrystalline TiO2 electrodes at surface coverages of 1.5 x 10-10 mol cm-2 and 4.9 x 10-11 mol cm-2, respectively. Finally, Me4Bpb-OH was converted to an amino derivative by attaching a diamino butane linker.